Gough's first role was with the Yew Tree Theatre production of Falling out of Love, written by John Breen and directed by Mikel Murfi. She has subsequently appeared in productions including Big Love for the Abbey Theatre, The Playboy of the Western World for the award-winning Druid Theatre Company, All in the Timing for Inis Theatre and Extremities for Spark to a Flame. More recent theatre work includes Lady Macbeth in 'Macbeth' directed by David Horan, Elizabeth in Don Carlos directed by Gadi Roll and Blanche in' Streetcar named Desire' directed by Chelsea Walker in what The Times called "a name-making performance".
Gough's extensive television credits include 'Strikeback', 'Call the Midwife','Broadchurch', 'The Fall','Casualty','Vera', 'Scup' ( for which she was nominated for the Actor of the Year Award at the Oireachtas Irish language media awards) The Clinic, This is Nightlive, and Raw'. . She has also appeared in the feature-length films 'Kill Command'and 'Out of Innocence'. Short films include 'Cry Rosa' and 'Taking Stock' for which she was nominated Best Actor in a female role at the Richard Harris International Film Festival.
- Smith, Andrea (18 November 2007). "Twins' kitchen sync drama". Irish Independent. Retrieved 2010-01-24.
- "Whats Hot For 2009?". Daily Mail. 3 January 2009. Archived from the original on 9 February 2010. Retrieved 2010-01-24.
https://www.thetimes.co.uk/article/theatre-review-a-streetcar-named-desire-at-nst-city-southampton-5zlw932gk https://www.independenttalent.com/actors/kelly-gough/ https://www.theguardian.com/stage/2018/mar/29/a-streetcar-named-desire-review-nuffield-southampton-theatres-city