Khusimol

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Khusimol
Khusimol.svg
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
UNII
  • InChI=1S/C15H24O/c1-10-13-5-4-12(9-16)15(13)7-6-11(8-15)14(10,2)3/h11-13,16H,1,4-9H2,2-3H3/t11-,12-,13-,15+/m1/s1
    Key: OOYRHNIVDZZGQV-BHPKHCPMSA-N
  • CC1(C2CCC3(C2)C(CCC3C1=C)CO)C
Properties
C15H24O
Molar mass 220.356 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Khusimol is a sesquiterpene found in oil of vetiver. It contains a tricyclic hydrocarbon core, with a hydroxy methyl group, two methyl groups and a methylene group.[1] It constitutes the biggest part of oil of vetiver, around 15%.[2] The substance was initially discovered by D. C. Umarani in 1966 and separatated by using distillation and column chromatography.[2]

References[edit]

  1. ^ Umarani, D.C.; Gore, K.G.; Chakravarti, K.K. (January 1966). "Terpenoids XC, Khusimol A New Sesquiterpene Alcohol". Tetrahedron Letters. 7 (12): 1255–1261. doi:10.1016/S0040-4039(01)99704-7.
  2. ^ a b Rao, Renee C.; Gal, Claudine Serradeil-Le; Granger, Isabelle; Gleye, Jacqueline; Augereau, Jean-Michel; Bessibes, Cecile (October 1994). "Khusimol, a Non-Peptide Ligand for Vasopressin V1a Receptors". Journal of Natural Products. 57 (10): 1329–1335. doi:10.1021/np50112a001. PMID 7807119.