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Kindling hypothesis

From Wikipedia, the free encyclopedia

Kindling hypothesis is the argument that some neurological and psychiatric conditions worsen due to repeated episodes of symptoms that cause neurological changes. These theories posit that if episodes continue without treatment, the threshold to trigger an epileptic seizure or mood episode in bipolar disorder will be lowered.[1]

References

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  1. ^ Post, Robert M. (2016). "The kindling/sensitization model and the pathophysiology of bipolar disorder". Bipolar Disorders: Basic Mechanisms and Therapeutic Implications (3 ed.). Cambridge University Press. pp. 204–218. ISBN 978-1-107-06271-9.