LIPH

From Wikipedia, the free encyclopedia
Jump to: navigation, search
LIPH
Identifiers
Aliases LIPH, AH, ARWH2, HYPT7, LAH2, LPDLR, PLA1B, mPA-PLA1, lipase H
External IDs MGI: 2388029 HomoloGene: 71802 GeneCards: LIPH
RNA expression pattern
PBB GE LIPH gnf1h05671 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_139248

NM_001083894
NM_001289581
NM_001289582
NM_153404

RefSeq (protein)

NP_640341

Location (UCSC) Chr 3: 185.51 – 185.55 Mb Chr 16: 21.95 – 22 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Lipase member H is an enzyme that in humans is encoded by the LIPH gene.[3][4][5]

This gene encodes a membrane-bound member of the mammalian triglyceride lipase family. It catalyzes the production of 2-acyl lysophosphatidic acid (LPA), which is a lipid mediator with diverse biological properties that include platelet aggregation, smooth muscle contraction, and stimulation of cell proliferation and motility.[5]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Jin W, Broedl UC, Monajemi H, Glick JM, Rader DJ (Sep 2002). "Lipase H, a new member of the triglyceride lipase family synthesized by the intestine". Genomics. 80 (3): 268–73. doi:10.1006/geno.2002.6837. PMID 12213196. 
  4. ^ Sonoda H, Aoki J, Hiramatsu T, Ishida M, Bandoh K, Nagai Y, Taguchi R, Inoue K, Arai H (Sep 2002). "A novel phosphatidic acid-selective phospholipase A1 that produces lysophosphatidic acid". J Biol Chem. 277 (37): 34254–63. doi:10.1074/jbc.M201659200. PMID 12063250. 
  5. ^ a b "Entrez Gene: LIPH lipase, member H". 

Further reading[edit]