In labile cells, it is not a speed-up in the segments of the cell cycle (i.e. G1 phase, S phase, G2 phase and M phase), but rather a short or absent G0 phase that is responsible for the cells' constant division.
Constantly dividing cells have a higher risk of becoming malignant and develop cancer, dividing uncontrollably. This is why, on the other hand, muscle cancer is very rare, although constituting ~50% of body weight, since muscle cells are not constantly dividing cells.
In addition, cytotoxic drugs, such as alkylating antineoplastic agents, used in treatment of cancer, work by inhibiting the proliferation of dividing cells, with the malignant cells as the desired target. However, this has the adverse effect of also striking against the cells normally dividing in the body, and thus impairing normal body function of hair, skin, GI tract and bone marrow.
- Stable cells, which only multiply when receiving external stimulus to do so
- Permanent cells, which don't have the ability to multiply
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