Late effect

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In medicine, a late effect is a condition that appears after the acute phase of an earlier, causal condition has run its course. A late effect can be caused directly by the earlier condition, or indirectly by the treatment for the earlier condition. Some late effects can occur decades later. Historically, late effects have been very difficult to connect with their causes, but as survivorship and life span has increased and "follow up" has become standard practice, these connections are becoming established. A period, often very long, of health unaffected by both the initial and the late effect conditions distinguishes a late effect from a sequela or a complication.


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  1. ^ "Late Effects". American Society of Clinical Oncology. 2010-10-14. Retrieved 2011-05-15. 
  2. ^ Johnston K, Vowels M, Carroll S, Neville K, Cohn R (2007). "Failure to lactate: A possible late effect of cranial radiation.". Pediatr Blood Cancer. 50 (3): 721. PMID 17763465. doi:10.1002/pbc.21291. 

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