Lisa Jones (scientist)
Lisa Jones | |
---|---|
Alma mater | Syracuse University Georgia State University |
Known for | Cell footprinting |
Scientific career | |
Institutions | University of Maryland Indiana University-Purdue University Indianapolis |
Lisa M. Jones is an Assistant Professor of Pharmaceutical Sciences at the University of Maryland, Baltimore.
Early life and education
Jones became interested in science as a freshman at high school, where she took part in a national Science Technology Engineering Program.[1] She went to college at Syracuse University, where she was the only person of colour.[2] Jones completed her PhD at Georgia State University and specialized in structural biology.[3]
Research and career
She was a Pfizer postdoctoral researcher at Washington University in St. Louis.[4][1] She joined Indiana University – Purdue University Indianapolis, where she became an Associate Professor.[5][6] In 2016 Jones won a $1.1 million National Science Foundation Career grant to develop new techniques to study cell membranes.[1] Her award supported research training for students from historically black colleges and universities to work in biochemistry.[1] She developed cell-footprinting, a technique that uses mass spectrometry coupled with in vivo fast photochemical oxidation of proteins (FPOP).[1][7][8] She is recognised as developing solving new questions in medicine as well as tools for biomedical researchers.[6]
She moved to the University of Maryland School of Pharmacy in 2016.[9] The Jones Lab is a structural proteomics group, who specialist in FPOP using an excimer laser for photolysis, which generates hydroxyl radicals.[10] Hydroxyl radicals go on to oxidise the side chains of amino acids and provide solvent accessibility of proteins within a cell.[11] FPOP can provide information on the sites of ligand binding, protein interaction and protein conformational changes.[10]
References
- ^ a b c d e "IUPUI chemist receives $1.1M NSF grant for research, training of minority future researchers: Newscenter: Indiana University–Purdue University Indianapolis". archive.news.iupui.edu. Retrieved 2018-04-22.
- ^ @Victoria08Davis, VICTORIA T. DAVIS. "IUPUI chemist awarded more than $1 million for research, training of minority students". Indianapolis Recorder Newspaper. Retrieved 2018-04-22.
{{cite news}}
: CS1 maint: numeric names: authors list (link) - ^ Chea, Emily E.; Jones, Lisa M. (2018-02-12). "Analyzing the structure of macromolecules in their native cellular environment using hydroxyl radical footprinting". Analyst. 143 (4). doi:10.1039/C7AN01323J. ISSN 1364-5528.
- ^ Jones, Lisa M.; Zhang, Hao; Vidavsky, Ilan; Gross, Michael L. (2010-02-15). "An On-Line, High-Pressure Digestion System for Protein Characterization by Hydrogen/Deuterium Exchange and Mass Spectrometry". Analytical Chemistry. 82 (4): 1171–1174. doi:10.1021/ac902477u. PMC 2826105. PMID 20095571.
- ^ "Lisa Jones". stem.indiana.edu. Retrieved 2018-04-22.
- ^ a b Brown, Alex. "IUPUI Professor Receives Lucrative Award". Retrieved 2018-04-22.
- ^ "NSF Award Search: Award#1701692 - CAREER: Development of an In Cell Footprinting Method for the Analysis of Protein Structure". www.nsf.gov. Retrieved 2018-04-22.
- ^ Rinas, Aimee; Mali, Vishaal S.; Espino, Jessica A.; Jones, Lisa M. (2016-10-07). "Development of a Microflow System for In-Cell Footprinting Coupled with Mass Spectrometry". Analytical Chemistry. 88 (20): 10052–10058. doi:10.1021/acs.analchem.6b02357.
- ^ "Its official! We're getting FPOP in Baltimore!". proteomicsnews.blogspot.co.uk. Retrieved 2018-04-22.
- ^ a b "Lisa Jones". faculty.rx.umaryland.edu. Retrieved 2018-04-22.
- ^ "Professor Lisa Jones - Indiana University" (PDF). University of Toledo. 2014-09-24. Retrieved 2018-04-22.
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