List of number-one R&B singles of 1946 (U.S.)
This list of R&B #1 hits of 1946 in the United States is part of the List of #1 R&B hits (USA).
| Issue Date | Song | Artist | Weeks at #1 |
| January 12 | "Buzz Me" | Louis Jordan and His Tympany Five | 9 weeks |
| March 16 | "Hey! Ba-Ba-Re-Bop" | Lionel Hampton and His Orchestra | 16 weeks* |
| March 23 | "Don’t Worry 'bout That Mule" | Louis Jordan and His Tympany Five | 1 week |
| June 29 | "The Gypsy" | The Ink Spots | 3 weeks* |
| July 10 | "Stone Cold Dead in the Market" | Ella Fitzgerald and Louis Jordan and His Tympany Five | 5 weeks |
| August 24 | "Choo Choo Ch'Boogie" | Louis Jordan and His Tympany Five | 18 weeks* |
| November 23 | "Ain’t That Just Like a Woman" | Louis Jordan and His Tympany Five | 2 weeks* |
An asterisk (*) after a song title means that the song lost and then regained the number-one spot.