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Lube may refer to:

  • Lubricant, a substance (usually a liquid) introduced between two moving surfaces to reduce the friction and wear between
  • Dura lube, produces engine treatment products for trucks and cars
  • Lube Motorcycles, former Spanish motorcycle manufacturer, based in Bilbao
  • Quaker Steak & Lube, a small, growing casual dining restaurant chain based in Sharon, Pennsylvania
  • Lube parish, an administrative unit of the Talsi District, Latvia
  • Lubeh, a Russian band, sometimes romanized as Lube
  • Volley Lube, an Italian volleyball club