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MAP4K5

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Template:PBB Mitogen-activated protein kinase kinase kinase kinase 5 is an enzyme that in humans is encoded by the MAP4K5 gene.[1][2][3]

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Interactions

MAP4K5 has been shown to interact with CRKL[4] and TRAF2.[5]

References

  1. ^ Tung RM, Blenis J (March 1997). "A novel human SPS1/STE20 homologue, KHS, activates Jun N-terminal kinase". Oncogene. 14 (6): 653–9. doi:10.1038/sj.onc.1200877. PMID 9038372.
  2. ^ Schultz SJ, Nigg EA (February 1994). "Identification of 21 novel human protein kinases, including 3 members of a family related to the cell cycle regulator nimA of Aspergillus nidulans". Cell Growth Differ. 4 (10): 821–30. PMID 8274451.
  3. ^ "Entrez Gene: MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5".
  4. ^ Shi, C S; Tuscano J; Kehrl J H (February 2000). "Adaptor proteins CRK and CRKL associate with the serine/threonine protein kinase GCKR promoting GCKR and SAPK activation". Blood. 95 (3). UNITED STATES: 776–82. ISSN 0006-4971. PMID 10648385. {{cite journal}}: Cite has empty unknown parameters: |laysummary=, |laydate=, and |laysource= (help)
  5. ^ Shi, C S; Leonardi A; Kyriakis J; Siebenlist U; Kehrl J H (September 1999). "TNF-mediated activation of the stress-activated protein kinase pathway: TNF receptor-associated factor 2 recruits and activates germinal center kinase related". J. Immunol. 163 (6). UNITED STATES: 3279–85. ISSN 0022-1767. PMID 10477597. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysource=, and |laysummary= (help)

Further reading

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