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MFT may refer to:
- Managed file transfer, a technology that supports secure transfer of files within and among organizations
- Quarterdeck Manifest, a DOS system diagnostics tool by Quarterdeck Office Systems
- Master File Table, an integral component of the NTFS file system
- Media Foundation Transform, a media processing plugin filter model in Microsoft Media Foundation
- Multiprogramming with a Fixed number of Tasks, an option of the OS/360 and successor operating systems
- Manchester University NHS Foundation Trust
- Marriage and Family Therapist
- Mean field theory
- Micro Four Thirds system, a standard for mirrorless interchangeable lens digital cameras and camcorders design and development.
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