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The following is a list of the MTV Europe Music Award winners and nominees for Best Act.
| Year | Category | Winner | Nominees |
|---|---|---|---|
| 2007 | Best Solo Act | Avril Lavigne | |
| 2008 | Best Act of 2008 | Britney Spears | |
| Best Act Ever | Rick Astley |
| Years | |
|---|---|
| Main categories |
|
| Regional and worldwide categories | |
| Defunct categories |
|
| Special Awards | |
| Nominations by nationality of artist | |
