Magnesium responsive RNA element
| Magnesium responsive RNA element | |
|---|---|
 | |
| Identifiers | |
| Symbol | Mg sensor |
| Rfam | RF01056 |
| Other data | |
| RNA type | Cis-regulatory element |
| Domain(s) | Enterobacteriales |
| GO | 0032026 |
| PDB structures | PDBe |
The Magnesium responsive RNA element, not to be confused with the completely distinct M-box riboswitch, is a cis-regulatory element that regulates the expression of the magnesium transporter protein MgtA. It is located in the 5' UTR of this gene.[1] The mechanism for the potential magnesium-sensing capacity of this RNA is still unclear, though a recent report suggests that the RNA element targets the mgtA transcript for degradation by RNase E when cells are grown in high Mg2+ environments.[2]
References
- ^ Groisman EA, Cromie MJ, Shi Y, Latifi T (2006). "A Mg2+-responding RNA that controls the expression of a Mg2+ transporter". Cold Spring Harb Symp Quant Biol. 71: 251–8. doi:10.1101/sqb.2006.71.005. PMID 17381304.
- ^ Spinelli SV, Pontel LB, García Véscovi E, Soncini FC (2008). "Regulation of magnesium homeostasis in Salmonella: Mg(2+) targets the mgtA transcript for degradation by RNase E.". FEMS Microbiol Lett. 280 (2): 226–34. doi:10.1111/j.1574-6968.2008.01065.x. PMID 18248433.
External links
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