Mahella-1 RNA motif
 | This article has multiple issues. Please help improve it or discuss these issues on the talk page. (Learn how and when to remove these messages)
|
| Mahella-1 | |
|---|---|
 Consensus secondary structure and sequence conservation of Mahella-1 RNA | |
| Identifiers | |
| Symbol | Mahella-1 |
| Rfam | RF03007 |
| Other data | |
| RNA type | Gene; sRNA |
| SO | SO:0001263 |
| PDB structures | PDBe |
The Mahella-1 RNA motif is a conserved RNA structure that was discovered by bioinformatics.[1] Seven Mahella-1 motif RNAs are found in Mahella australiensis, and no other organism has been (as of 2018) observed to contain Mahella-1 RNAs.
All seven Mahella-1 RNAs are located upstream of protein-coding genes, which could suggest that the RNAs function as cis-regulatory elements. However, it is unusual that 6 non-homologous genes are found downstream of Mahella-1 RNAs, and that these genes do not seem related to each other. cis-regulatory RNAs are generally located upstream of characteristic gene classes. Thus, Mahella-1 RNAs might correspond to small RNAs, or have some other function.
References
[edit]- ^ Weinberg Z, Lünse CE, Corbino KA, Ames TD, Nelson JW, Roth A, et al. (October 2017). "Detection of 224 candidate structured RNAs by comparative analysis of specific subsets of intergenic regions". Nucleic Acids Research. 45 (18): 10811–10823. doi:10.1093/nar/gkx699. PMC 5737381. PMID 28977401.