It may refer to:
- Megali Panagia, Chalkidiki, a village in Chalkidiki peninsula and seat of old Panagia municipality.
- Church of Megali Panagia, a church built on the site of Hadrian's Library in Athens, now in ruins
- Monastery of Megali Panagia (built in 1586) near the village of Koumaradaioi on the island of Samos
disambiguation page lists articles associated with the title Megali Panagia.
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