The manor of Middeltone was donated at some time before the Norman Conquest of 1066 (according to the Devon historian Risdon (d. 1640) by "a knight that dwelt in Daversweek") to Tavistock Abbey, as is recorded in the Domesday Book of 1086, and, together with most of the abbey's other extensive possessions, was acquired following the Dissolution of the Monasteries by John Russell, 1st Earl of Bedford (c.1485-1554/5), appointed Lord Lieutenant of Devon by King Henry VIII. In 1810 the manor was owned by his descendant John Russell, 6th Duke of Bedford (1766–1839).
In the parish is Endsleigh Cottage, built between 1810 and 1816 by John Russell, 6th Duke of Bedford of Woburn Abbey in Bedfordshire, as a private family residence, to the designs of Sir Jeffry Wyatville, in the style of the picturesque movement, a grand form of the cottage orné, now a hotel.
The estate of Edgcumbe within the parish was the original English seat of the Edgcumbe family (originally de Edgecumbe), a branch of which was created Earl of Mount Edgcumbe in 1789, seated at Mount Edgcumbe House in Cornwall.
- Risdon, Tristram (d.1640), Survey of Devon, 1811 edition, London, 1811, with 1810 Additions, p.218
- Thorn, Caroline & Frank, (eds.) Domesday Book, (Morris, John, gen.ed.) Vol. 9, Devon, Parts 1 & 2, Phillimore Press, Chichester, 1985, Chapter 5,2
- Pole, Sir William (d.1635), Collections Towards a Description of the County of Devon, Sir John-William de la Pole (ed.), London, 1791, p.343
- Risdon, 1810 Additions, p.404
- Vivian, Lt.Col. J.L., (Ed.) The Visitations of the County of Devon: Comprising the Heralds' Visitations of 1531, 1564 & 1620, Exeter, 1895, p.324, pedigree of Edgcumbe; Edgcumbe, Milton Abbot, per Pevsner, Nikolaus & Cherry, Bridget, The Buildings of England: Devon, London, 2004, p.569; Vivian, p.319: "Edgcombetowne in the parish of Milton"