Mr. Big may refer to:
In film and literature
- Mister Big (James Bond), a villain in the novel and film Live and Let Die
- Mister Big (1943 film)
- Mr. Big (film), a 2007 documentary
- Mr. Big, a character on the 1970s TVOntario children's television series Math Patrol
- Mr Big, a 1977 BBC TV sitcom written by and starring Peter Jones
- Mister Big (Rocky and Bullwinkle), a villain from the Rocky and Bullwinkle cartoons
- Mr. Big (Sex and the City), a character from the Sex and the City television series and movie
- Mr. Big, pseudonym used by Hank Hill in the King of the Hill episode "Soldier of Misfortune"
In video games
- Mr. Big (Art of Fighting), a character originally from the Art of Fighting video game series
- Mister Big, a ghost boss from the video game Draconus: Cult of the Wyrm
- Mr. Big, the main villain from the motion picture and video game Michael Jackson's Moonwalker
- Mr. Big, a villain from the video game NARC
- Mr. Big, a character from the animated series WordGirl
- "Mr. Big" (song), a song by Free, later covered by Mr. Big the American band
- Cadbury Mr. Big, a brand of chocolate bar
- Mr Big, a slang term for a highly ranked person within an organised crime organisation
- Mr. Big (police procedure), a method used by undercover police in Canada and Australia to obtain confessions from cold cases
- Mr Big, the name of the balloon involved in the 2012 Carterton hot air balloon crash in New Zealand
- Mr Big, a nickname for the New Zealand heroin trafficker and murderer Terrance John Clark
- Big (disambiguation)
- Mr Bigg's, a fast food chain in Ghana and Nigeria
- Ronald Isley, an American soul single occasionally known as "Mr. Biggs"
|This disambiguation page lists articles associated with the title Mr. Big.
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