Myospherulosis
Appearance
Myospherulosis, also known as spherulocytosis,[1] is a foreign body-type granulomatous reaction to lipid-containing material and blood.[1][2]
It may be seen in various settings including:
- Fat necrosis.[1]
- Malignancy, e.g. renal cell carcinoma.[3]
- Placement of topical tetracycline in a petrolatum base into a surgical site.
The resultant histopathologic pattern is most unusual and initially was mistakenly thought to represent a previously undescribed endosporulating fungus.
See also
References
- ^ a b c Godbersen, GS.; Kleeberg, J.; Lüttges, J.; Werner, JA. (Sep 1995). "[Spherulocytosis (myospherulosis) of the paranasal sinuses]". HNO. 43 (9): 552–5. PMID 7591868.
- ^ Fisher, SC.; Horning, GM.; Hellstein, JW. (Dec 2001). "Myospherulosis complicating cortical block grafting: a case report". J Periodontol. 72 (12): 1755–9. doi:10.1902/jop.2001.72.12.1755. PMID 11811513.
- ^ Chau, KY.; Pretorius, JM.; Stewart, AW. (Oct 2000). "Myospherulosis in renal cell carcinoma". Arch Pathol Lab Med. 124 (10): 1476–9. doi:10.1043/0003-9985(2000)124<1476:MIRCC>2.0.CO;2. PMID 11035579.