Natalie Ahn

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Natalie G. Ahn
Fields Chemistry
Institutions University of Colorado at Boulder (1992– )
University of Colorado Health Sciences Center, Denver (2003– )
Howard Hughes Medical Institute (1994–2014 )
Alma mater University of Washington, Seattle (B.S., 1979)
University of California, Berkeley (Ph.D., 1985)
Doctoral advisor Judith P. Klinman
Other academic advisors Edwin Krebs
Christoph de Haën

Natalie G. Ahn Ph.D. is a Professor of Chemistry and Biochemistry at the University of Colorado at Boulder. Her research is focused understanding the mechanisms of cell signaling, especially in relation to phosphorylation and cancers.[1] Ahn's work uses the tools of "classical chemistry" to work on understanding the genetic code and how genetics affects life processes.[2] She has been a professor at University of Colorado at Boulder since 2003, where she is a Professor of Distinction.[3] She was a Howard Hughes Medical Institute (HHMI) investigator between 1994 and 2014.[4]


Ahn earned her bachelor's degree from the University of Washington, Seattle in 1979.[5] In 1985, she completed her PhD at the University of California, Berkeley.[5] She started working at CU-Boulder in 1992.[6] Ahn was part of the Searle Scholars Program to fund young scientists' work in 1993.[7]

Ahn was one of eight project collaborators who won a grant from the W.M. Keck Foundation for identifying proteins in a single cell type.[8] In 2012, she was named College Professor of Distinction at the University of Colorado.[6] In 2014, she became part of the Subcellular Pan-Omics for Advanced Rapid Threat Assessment (SPARTA) team which is a biochemical project supported by the Defense Advanced Research Projects Agency (DARPA).[9] Ahn is published in BMC Bioinformatics,[10] Science,[11] The EMBO Journal,[12] the International Journal of Mass Spectrometry,[13] Molecular and Cellular Biochemistry,[14] and others.



  1. ^ "New method for detection of phosphoproteins reveals regulator of melanoma invasion". Clinical Oncology Week. 27 April 2009. Retrieved 15 January 2016 – via HighBeam Research. (subscription required (help)). 
  2. ^ Friedman, Roberta (January 2004). "Finding the Trees in the Proteomic Forest". Genomics & Proteomics. 4 (1): 38–40. Retrieved 15 January 2016 – via EBSCO. (subscription required (help)). 
  3. ^ "Natlie G. Ahn". University of Colorado Boulder. Retrieved 15 January 2016. 
  4. ^ "Natalie G. Ahn, PhD". Howard Hughes Medical Institute. Retrieved 15 January 2016. 
  5. ^ a b "Natalie Ahn". BioFrontiers Institute. University of Colorado. Retrieved 15 January 2016. 
  6. ^ a b Talbott, Clint (2013). "Following the Pathways to Metastatic Melanoma". Colorado Arts and Sciences Magazine. University of Colorado Boulder. Retrieved 15 January 2016. 
  7. ^ "Natalie G. Ahn". Searle Scholars Program. Retrieved 15 January 2016. 
  8. ^ "CU People – September 2009". Coloradan Magazine. September 2009. Retrieved 15 January 2016. 
  9. ^ "CU Awarded DARPA Cooperative Agreement to Assess Mechanisms of Drugs and Chemical Agents". Biotech Week. 12 February 2014. Retrieved 15 January 2016 – via HighBeam Research. (subscription required (help)). 
  10. ^ Gehrke, Allison; Sun, Shaojun; Kurgan, Lukasz; Ahn, Natalie; Resing, Katheryn; Kafadar, Karen; Cios, Krzysztof (2008). "Improved machine learning method for analysis of gas phase chemistry of peptides". BMC Bioinformatics. Retrieved 15 January 2016. 
  11. ^ Duesbery, Nicholas S.; Webb, Craig P.; Leppla, Stephen H.; Gordon, Valery M.; Klimpel, Kurt R.; Copeland, Terry D.; Ahn, Natalie G.; Oskarsson, Marianne K.; Fukasawa, Kenji (1998-05-01). "Proteolytic Inactivation of MAP-Kinase-Kinase by Anthrax Lethal Factor". Science. 280 (5364): 734–737. doi:10.1126/science.280.5364.734. ISSN 0036-8075. PMID 9563949. 
  12. ^ Frost, Jeffrey A.; Steen, Helge; Shapiro, Paul; Lewis, Tim; Ahn, Natalie; Shaw, Peter E.; Cobb, Melanie H. (1997). "Cross-cascade activation of ERKs and ternary complex factors by Rho family proteins" (PDF). The EMBO Journal. 16 (21): 6426–6438. doi:10.1093/emboj/16.21.6426. PMC 1170249free to read. Retrieved 15 January 2016. 
  13. ^ Ring, Adam Y.; Sours, Kevin M.; Lee, Thomas; Ahn, Natalie G. (2011-04-30). "Distinct patterns of activation-dependent changes in conformational mobility between ERK1 and ERK2". International Journal of Mass Spectrometry. Hydrogen Exchange Mass Spectrometry. 302 (1–3): 101–109. doi:10.1016/j.ijms.2010.08.020. PMC 3139246free to read. PMID 21785572. 
  14. ^ Ahn, Natalie G. (1993). "The Map Kinase Cascade. Discovery of a New Signal Transduction Pathway". Molecular and Cellular Biochemistry. 127: 201–209. Retrieved 15 January 2016. 

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