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Nuclear moulding

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Micrograph of a small cell carcinoma showing cells with nuclear moulding. FNA specimen. Field stain.

In histopathology, nuclear moulding, also nuclear molding, is conformity of adjacent cell nuclei to one another.[1]

It is a feature of small cell carcinomas and particularly useful for differentiation of small cell and non-small cell carcinomas, i.e. adenocarcinoma and squamous carcinoma.[2]

See also

References

  1. ^ http://www.vet.ohio-state.edu/assets/courses/vm618/gloss/glossary.html
  2. ^ Cakir, E.; Demirag, F.; Aydin, M. (Feb 2010). "Cytopathologic differential diagnosis of small cell carcinoma and poorly differentiated non-small cell carcinoma in bronchial lavage specimens using a regression analysis". APMIS. 118 (2): 150–5. doi:10.1111/j.1600-0463.2009.02575.x. PMID 20132179.
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