NuoG RNA motif

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nuoG RNA
Consensus secondary structure of nuoG RNAs
Symbol nuoG RNA
Rfam RF01748
Other data
RNA type Cis-regulatory element
Domain(s) Enterobacteria

The nuoG RNA motif is a conserved RNA structure detected by bioinformatics.[1] It is located in the presumed 5' untranslated regions of nuoG genes. This gene and the downstream genes probably comprise an operon that encodes various subunits of ubiquinone reductase enzyme.

nuoG RNAs are found only in some, but not all, enterobacteria. There is a question of whether sequences in the genus Salmonella correspond to nuoG RNAs that do not conserve the proposed secondary structure. If so, this observation would undermine the proposed conserved structure. However, the similarity in sequence between the recognized nuoG RNAs and the Salmonella sequences is loose, and so the sequences might be unrelated. Because of the question of the Salmonella sequences, some ambiguity remains as to whether or not nuoG RNAs do, in fact, function as structured RNAs.[1]


  1. ^ a b Weinberg Z, Wang JX, Bogue J, et al. (March 2010). "Comparative genomics reveals 104 candidate structured RNAs from bacteria, archaea and their metagenomes". Genome Biol. 11 (3): R31. PMC 2864571Freely accessible. PMID 20230605. doi:10.1186/gb-2010-11-3-r31. 

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