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The term papilla (plural: papillae) generally means a nipple-like structure, and may refer to:
- Mammary papilla, or nipple
- Amphibian papilla and basal papilla, part of the inner ear of the frog.
- Interdental papilla, part of the gingiva between teeth
- Dental papilla, cells involved in a developing tooth
- Genital papilla, a small tube in some animals through which eggs or sperm are released
- Renal papilla, in the kidney
- Lacrimal papilla, on the eyelid
- Major duodenal papilla, the opening of the pancreatic duct and common bile duct into the duodenum
- Minor duodenal papilla, the opening of the accessory pancreatic duct into the duodenum
- Dermal papillae, at the base of every hair follicle
- Papillary thyroid cancer, a type of disease
- Papilloma, a benign epithelial tumor
- Papillary muscle, a muscle in the heart
- Cuticular papilla, a raised thickening in plant cuticle, not large enough to be considered a trichome or hair.
- Lingual papillae, of which there are 4 types:
- Papilla (fish anatomy), small lumps of dermal tissue found in the mouth which hold taste buds
- The sensory papillae of the Amblyopsidae (cavefishes)
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