Pethidine intermediate A

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Pethidine intermediate A
Systematic (IUPAC) name
Clinical data
Legal status
Routes of
CAS Registry Number 3627-62-1
ATC code None
PubChem CID: 62513
Chemical data
Formula C13H16N2
Molecular mass 200.28 g/mol
 YesY (what is this?)  (verify)

Pethidine intermediate A is a 4-phenylpiperidine derivative that is a precursor to the opioid analgesic drug pethidine (meperidine). It is not known to have any analgesic activity in its own right, however other derivatives of pethidine with a 4-cyano group in place of the carboxylate ethyl ester have been found to be active,[1] so pethidine intermediate A might also show opioid effects. It is scheduled by UN Single Convention on Narcotic Drugs.

See also[edit]


  1. ^ Lomenzo SA, Rhoden JB, Izenwasser S, Wade D, Kopajtic T, Katz JL, Trudell ML. Synthesis and Biological Evaluation of Meperidine Analogues at Monoamine Transporters. Journal of Medicinal Chemistry. 2005; 48:1336-1343.