Phonophoresis is the use of ultrasound to enhance the delivery of topically applied drugs. Phonophoresis has been used in an effort to enhance the absorption of topically applied analgesics and anti-inflammatory agents through the therapeutic application of ultrasound.
Phonophoresis has been shown to be ineffective for some treatments, where it did not increase the efficacy of absorption of drugs, or did not improve the outcome more than the use of ultrasound alone.
- Bare AC, McAnaw MB, Pritchard AE, et al. (July 1996). "Phonophoretic delivery of 10% hydrocortisone through the epidermis of humans as determined by serum cortisol concentrations". Phys Ther. 76 (7): 738–45; discussion 746–9. PMID 8677278.
- Byl NN (June 1995). "The use of ultrasound as an enhancer for transcutaneous drug delivery: phonophoresis". Phys Ther. 75 (6): 539–53. PMID 7770499.
- Gogstetter DS, Goldsmith LA (May 1999). "Treatment of cutaneous sarcoidosis using phonophoresis". J. Am. Acad. Dermatol. 40 (5 Pt 1): 767–9. PMID 10321609. doi:10.1016/S0190-9622(99)70162-3.
- Srbely JZ. "Ultrasound in the management of osteoarthritis: part I: a review of the current literature". JCCA J Can Chiropr Assoc. 52 (1): 30–.
- Hoppenrath T, Ciccone CD (January 2006). "Is there evidence that phonophoresis is more effective than ultrasound in treating pain associated with lateral epicondylitis?". Phys Ther. 86 (1): 136–40. PMID 16386068.
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