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Phonophoresis procedure

Phonophoresis is the use of ultrasound to enhance the delivery of topically applied drugs.[1][2] Phonophoresis has been used in an effort to enhance the absorption of topically applied analgesics and anti-inflammatory agents through the therapeutic application of ultrasound.

Phonophoresis has been shown to be ineffective for some treatments,[3] where it did not increase the efficacy of absorption of drugs, or did not improve the outcome more than the use of ultrasound alone.[4][5]

See also[edit]


  1. ^ Skauen, Donald M.; Zentner, Gaylen M. (1984). "Phonophoresis". International Journal of Pharmaceutics. 20 (3): 235–245. doi:10.1016/0378-5173(84)90171-6. ISSN 0378-5173.
  2. ^ Tyle, Praveen; Agrawala, Praful (1989). "Drug Delivery by Phonophoresis". Pharmaceutical Research. 06 (5): 355–361. doi:10.1023/A:1015967012253. ISSN 0724-8741. PMID 2664754. S2CID 30836255.
  3. ^
  4. ^ Klaiman, Mark D.; Shrader, Joseph A.; Danoff, Jerome V.; Hicks, Jeanne E.; Pesce, William J.; Ferland, James (1998). "Phonophoresis versus ultrasound in the treatment of common musculoskeletal conditions". Medicine & Science in Sports & Exercise. 30 (9): 1349–1355. doi:10.1097/00005768-199809000-00002. ISSN 0195-9131. PMID 9741602.
  5. ^ Ay, Saime; Doğan, Şebnem Koldaş; Evcik, Deniz; Başer, Özgün Çakmak (2010). "Comparison the efficacy of phonophoresis and ultrasound therapy in myofascial pain syndrome". Rheumatology International. 31 (9): 1203–1208. doi:10.1007/s00296-010-1419-0. ISSN 0172-8172. PMID 20354859. S2CID 318661.

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