Pleurocidin

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Antimicrobial12
Identifiers
Symbol Antimicrobial12
Pfam PF08107
InterPro IPR012515
TCDB 1.C.62
OPM superfamily 310
OPM protein 1z64

Pleurocidin is an antimicrobial peptide found in the mucus secreted by the skin of the winter flounder (Pleuronectes americanus). It exhibits broad-spectrum antimicrobial activity.[1] Pleurocidin assumes an amphipathic alpha-helical conformation similar to other linear antimicrobial peptides and may play a role in innate host defence.[2]

References[edit]

  1. ^ Burrowes, O. J.; Hadjicharalambous, C.; Diamond, G.; Lee, Tung-Ching (2004-04-01). "Evaluation of Antimicrobial Spectrum and Cytotoxic Activity of Pleurocidin for Food Applications". Journal of Food Science. 69 (3): FMS66–FMS71. doi:10.1111/j.1365-2621.2004.tb13373.x. ISSN 1750-3841. 
  2. ^ Cole AM, Weis P, Diamond G (May 1997). "Isolation and characterization of pleurocidin, an antimicrobial peptide in the skin secretions of winter flounder". J. Biol. Chem. 272 (18): 12008–13. doi:10.1074/jbc.272.18.12008. PMID 9115266. 

This article incorporates text from the public domain Pfam and InterPro IPR012515