Benzylpenicilloyl polylysine

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Benzylpenicilloyl polylysine
Benzylpenicilloyl polylysine (structural diagram).png
Clinical data
Trade names Pre-Pen
Synonyms Pre-Pen
License data
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Liquid intradermal
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Legal status
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Benzylpenicilloyl polylysine (Pre-Pen) is used as a skin test before the administration of penicillin. It is used to detect the immunoglobulin E antibodies.[1][2] The chemical structure consists of the benzylpenicilloyl group attached to a polymer of L-lysine.[3][4][5]


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  3. ^ Vemuri, Preeti; Harris, Kathleen E.; Suh, Lydia A.; Grammer, Leslie C. (2004). "Preparation of benzylpenicilloyl-polylysine: a preliminary study". Allergy and Asthma Proceedings. 25 (3): 165–168. 
  4. ^ Goldschmidt, BM; BB Levine (1983). "The preparation and determination of structure of benzylpenicilloyl compounds used in skin-testing for penicillin allergy". Journal of Antibiotics. 36 (6): 709–14. doi:10.7164/antibiotics.36.709. PMID 6874593. 
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