Propyleneimine

Propyleneimine
Names
	IUPAC name 2-Methylaziridine
	Other names 1,2-Propylenimine
Identifiers
CAS Number	75-55-8;
3D model (JSmol)	Interactive image;
ChemSpider	6137;
ECHA InfoCard	100.000.799
EC Number	613-033-00-6;
PubChem CID	6377;
RTECS number	CM8050000;
UN number	1921 (inhibited)
CompTox Dashboard (EPA)	DTXSID8024286 ;
	InChI InChI=1S/C3H7N/c1-3-2-4-3/h3-4H,2H2,1H3 Key: OZDGMOYKSFPLSE-UHFFFAOYSA-N; InChI=1/C3H7N/c1-3-2-4-3/h3-4H,2H2,1H3 Key: OZDGMOYKSFPLSE-UHFFFAOYAW;
	SMILES N1C(C)C1;
Properties
Chemical formula	C3H7N
Molar mass	57.096 g·mol−1
Appearance	Colorless, oily liquid
Odor	ammonia-like
Density	0.9 g/mL
Melting point	−63 °C (−81 °F; 210 K)
Boiling point	67 °C (153 °F; 340 K)
Solubility in water	Miscible
Vapor pressure	112 mmHg (20°C)
Hazards
Flash point	−4 °C (25 °F; 269 K)
	Lethal dose or concentration (LD, LC):
LCLo (lowest published)	500 ppm (rat, 4 hr)
	NIOSH (US health exposure limits):
PEL (Permissible)	TWA 2 ppm (5 mg/m3) [skin]
REL (Recommended)	Ca TWA 2 ppm (5 mg/m3) [skin]
IDLH (Immediate danger)	Ca [100 ppm]
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Propyleneimine is the organic compound with the formula CH₃CH(NH)CH₂. It is a secondary amine]] and the smallest chiral aziridine (ring containing C₂N). It is a colorless liquid.

The compound is mainly of academic interest, e.g. for the synthesis of dendrimers, a process that exploits the tendency of aziridines to undergo ring-opening reactions.^[4] ^[2]

References

^ ^a ^b ^c ^d ^e ^f NIOSH Pocket Guide to Chemical Hazards. "#0537". National Institute for Occupational Safety and Health (NIOSH).
^ ^a ^b ^c ^d ^e ^f ^g ^h Propyleneimine International Chemical Safety Card at actrav.itcilo.org
^ "Propylene imine". Immediately Dangerous to Life or Health Concentrations (IDLH). National Institute for Occupational Safety and Health (NIOSH).
^ "Dendrimers: Relationship between structure and biocompatibility in vitro, and preliminary studies on the biodistribution of 125I-labeled polyamidoamine dendrimers in vivo". Journal of Controlled Release. 65: 133–148. 2000. doi:10.1016/S0168-3659(99)00246-1. {{cite journal}}: Unknown parameter |authors= ignored (help)

This article about a heterocyclic compound is a stub. You can help Wikipedia by expanding it.

[PGCH-1] ^ ^a ^b ^c ^d ^e ^f NIOSH Pocket Guide to Chemical Hazards. "#0537". National Institute for Occupational Safety and Health (NIOSH).

[ICSC-2] ^ ^a ^b ^c ^d ^e ^f ^g ^h Propyleneimine International Chemical Safety Card at actrav.itcilo.org

[3] "Propylene imine". Immediately Dangerous to Life or Health Concentrations (IDLH). National Institute for Occupational Safety and Health (NIOSH).

[4] "Dendrimers: Relationship between structure and biocompatibility in vitro, and preliminary studies on the biodistribution of 125I-labeled polyamidoamine dendrimers in vivo". Journal of Controlled Release. 65: 133–148. 2000. doi:10.1016/S0168-3659(99)00246-1. {{cite journal}}: Unknown parameter |authors= ignored (help)

[1]

[2]

[3]

[4]