Pseudohypoxia

Pseudohypoxia refers to increased cytosolic ratio of free NADH to NAD in cells.^[1] Research has shown that declining levels of NAD+ during aging cause pseudohypoxia, and that raising nuclear NAD+ in old mice reverses pseudohypoxia and metabolic dysfunction, thus reversing the aging process.^[2] It is expected that human NAD trials will begin in 2014.^[3]

References

^ [1] Diabetes Magazine: Hyperglycemic Pseudohypoxia and Diabetic Complications, March 12, 1993
^ [2] Declining NAD+ Induces a Pseudohypoxic State Disrupting Nuclear-Mitochondrial Communication during Aging, Cell, Dec 2013
^ [3] Guardian Newspaper - Online, Dec 2013

This article about a disease, disorder, or medical condition is a stub. You can help Wikipedia by expanding it.

[1] [1] Diabetes Magazine: Hyperglycemic Pseudohypoxia and Diabetic Complications, March 12, 1993

[2] [2] Declining NAD+ Induces a Pseudohypoxic State Disrupting Nuclear-Mitochondrial Communication during Aging, Cell, Dec 2013

[3] [3] Guardian Newspaper - Online, Dec 2013

[1]

[2]

[3]

See also

References