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Roff may refer to:
- Derek Roff, Canadian biologist
- Don Roff (born 1966), American writer and filmmaker
- Jeremy Roff (born 1983), Australian middle-distance runner
- Joe Roff (born 1975), Australian rugby union player
- Rosie Roff (born 1989), British ring girl and model
disambiguation page lists articles associated with the title Roff.
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