SELT
Template:PBB Selenoprotein T, also known as SELT, is a protein that in humans is encoded by the SELT gene.[1][2][3]
Gene
The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal.[3]
Protein structure
Selenoprotein T contains a selenocysteine (Sec) residue at its active site.
See also
References
- ^ Kryukov GV, Kryukov VM, Gladyshev VN (November 1999). "New mammalian selenocysteine-containing proteins identified with an algorithm that searches for selenocysteine insertion sequence elements". J. Biol. Chem. 274 (48): 33888–97. doi:10.1074/jbc.274.48.33888. PMID 10567350.
{{cite journal}}: CS1 maint: multiple names: authors list (link) CS1 maint: unflagged free DOI (link) - ^ Kryukov GV, Castellano S, Novoselov SV, Lobanov AV, Zehtab O, Guigó R, Gladyshev VN (May 2003). "Characterization of mammalian selenoproteomes". Science. 300 (5624): 1439–43. doi:10.1126/science.1083516. PMID 12775843.
{{cite journal}}: CS1 maint: multiple names: authors list (link) - ^ a b "Entrez Gene: SELT selenoprotein T".
Further reading
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