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Sally was born in Watertown, New York. She studied painting at the State University of New York at Albany and later studied art at Hunter College in New York where her tutors included Tony Smith (sculptor) and Robert Morris.
She is a prolific painter and committed to a rigorous work schedule. Her works have included an interactive touring exhibition in association with the University of Hertfordshire called the Wishing Ceremony. The Wishing Ceremony opened in six locations in Leicester City in 2005 and then traveled to the University of Hertfordshire and mac in Birmingham in 2006. The Wishing Ceremony is also available on-line as part of an interactive website.
Her exhibitions include Sacred Vessels at Rugby Art Gallery and Museum in Rugby, 2003; Days at The Gallery in Stratford-upon-Avon, 2002); The Naming Room at Roadmender, Northampton, 2001); Fragments of Time and Thought at Liberty (department store), London, 2000), Artjongg at the University College Northampton; Between the Lines (Ikon Touring, Birmingham 1997); and New Work (City Gallery, Leicester, 1995). Commissions include Non-Essential Signage for Arts Council England, Announcements for South and East Belfast Trust, Artkacina for firstsite in Colchester (2006) and ARTDNA for Towner in Eastbourne (2008).
In 2010 Sally finished her latest work, Let's Celebrate - a new commission inspired by the London 2012 Olympic and Paralympic games. The work toured to five National Trust properties across the East Midlands throughout 2010. Comprising over 250 painted sculptures, this participatory artwork invited visitors to consider and record what they want to celebrate in life, adding their written celebrations to the installation.
Most recently Sally has worked on a project created in collaboration with researchers at The Wellcome Trust Sanger Institute in Cambridge  and funded by the National Trust, Mottisfont Abbey. This work, Being Human considered the unique make-up of humanity; what makes each and everyone of us different and equally special. The work was displayed at Mottisfont Abbey in the Autumn of 2011.
Sally Sheinman is also involved with Artists Interaction and Representation (AIR) and has recently been elected as Chair of this organisation which represents over 16,000 artists within the UK.
- "New exhibition shows some choice cuts from paper artists". Romsey Advertiser. 10 November 2011. Retrieved 11 May 2012.