Sclerosis (medicine)

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Sclerosis (medicine)
Lichen sclerosus - very high mag.jpg
Micrograph of subepithelial sclerosus (middle third of image) in a case of lichen sclerosus. H&E stain.
Classification and external resources

In medicine, sclerosis (also spelled sclerosus in the names of a few disorders; from Greek σκληρός "hard") is the stiffening of a structure, usually caused by a replacement of the normal organ-specific tissue with connective tissue. The structure may be said to have undergone sclerotic changes or display sclerotic lesions, which refers to the process of sclerosis.

Common medical conditions whose pathology involves sclerosis include:


  1. ^ "Welcome To The NephCure Foundation". Archived from the original on 2009-06-02.
  2. ^ "Focal sclerosis definition - Medical Dictionary definitions of popular medical terms easily defined on MedTerms". 2012-09-20. Retrieved 2013-01-12.