Sclerosis (medicine)

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Sclerosis (medicine)
Lichen sclerosus - very high mag.jpg
Micrograph of subepithelial sclerosus (middle third of image) in a case of lichen sclerosus. H&E stain.
Classification and external resources
MeSH D012598

In medicine, sclerosis (also spelled sclerosus in the names of a few disorders; from Greek σκληρός "hard") is the stiffening of a structure, usually caused by a replacement of the normal organ-specific tissue with connective tissue. The structure may be said to have undergone sclerotic changes or display sclerotic lesions, which refers to the process of sclerosis.

Common medical conditions whose pathology involves sclerosis include:

Note that liver 'sclerosis' is a common misspelling or mispronunciation of cirrhosis of the liver.

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