Siewert classification

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The Siewert-Stein classification (often called the Siewert classification in less precise shorthand reference) is a system of anatomical classification used for adenocarcinomas of the esophagogastric junction.


Type I[edit]

Adenocarcinoma of the distal part of the esophagus. The tumor center is located 1–5 cm above the gastric cardia.

Type II[edit]

Adenocarcinoma of the real cardia. The tumor center is located 1 cm above or 2 cm below the gastric cardia. Considered to be true gastroesophageal junction.

Type III[edit]

Adenocarcinoma of the subcardial stomach. The tumor center is located 2–5 cm below the gastric cardia.[1][2]


  1. ^ Siewert JR, Stein HJ. Carcinoma of the cardia: carcinoma of the gastroesophageal junction—classification, pathology and extent of resection. Dis Esophagus 1996;9:173-82.
  2. ^ Schneider, Paul M.; Mönig, Stefan P. (2017), "Siewert Classification of Adenocarcinoma of the Esophagogastric Junction: Still In or Already Out?", Adenocarcinoma of the Esophagogastric Junction, Springer International Publishing, pp. 47–56, doi:10.1007/978-3-319-28776-8_7, ISBN 9783319287744