Simon Wain-Hobson

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Simon Wain-Hobson OBE (born 25 May 1953) is a British/French Microbiologist, Professor of Molecular Retrovirology at the Pasteur Institute in Paris, Director of the French National HPV Reference Laboratory, and Board Chairman of the Foundation for Vaccine Research in Washington, D.C.


Wain-Hobson obtained a PhD in Biochemistry from the University of Oxford in 1977, served as a post-doctoral fellow at the Weizmann Institute of Science from 1977 to 1980, and thereafter moved to the Pasteur Institute in Paris. Wain-Hobson and his research group at the Pasteur Institute were the first to publish the sequence of HIV, which was also the first full sequence of a primate lentivirus.[1][2] Wain-Hobson is holder of licensed patents on HIV genomes and diagnostics.[3]

Wain-Hobson's most recent work involves the role of APOBEC3 in cancer and other human diseases.[4][5] Wain-Hobson is a co-founder of Invectys Inc., a biopharmaceutical company focused on the development of immunotherapy approaches to the treatment of cancer.

Wain-Hobson won the André Lwoff prize in 1996 and Athena prize from the French Academy of Sciences in 2007 and is Officier de la Légion d’Honneur.[6]

Wain-Hobson was appointed Officer of the Order of the British Empire (OBE) in the 2022 New Year Honours for services to virology.[7]


  1. ^ Wain-Hobson, S. (1995). "An interview with Simon Wain-Hobson, PHD. Interview by Mark Mascolini". Journal of the International Association of Physicians in AIDS Care. 1 (4): 8–13. PMID 11362509.
  2. ^ "A retroviral mystery tour". 28 November 2019.
  3. ^ "Bio". Retrieved 2021-06-07.
  4. ^ Perez-Bercoff, Danielle; Laude, Hélène; Lemaire, Morgane; Hunewald, Oliver; Thiers, Valérie; Vignuzzi, Marco; Blanc, Hervé; Poli, Aurélie; Amoura, Zahir; Caval, Vincent; Suspène, Rodolphe; Hafezi, François; Mathian, Alexis; Vartanian, Jean-Pierre; Wain-Hobson, Simon (12 April 2021). "Sustained high expression of multiple APOBEC3 cytidine deaminases in systemic lupus erythematosus". Scientific Reports. 11 (1): 7893. doi:10.1038/s41598-021-87024-1. ISSN 2045-2322. PMC 8041901. Retrieved 2 November 2021.
  5. ^ Vartanian, Jean-Pierre; Guétard, Denise; Henry, Michel; Wain-Hobson, Simon (11 April 2008). "Evidence for Editing of Human Papillomavirus DNA by APOBEC3 in Benign and Precancerous Lesions". Science. 320 (5873): 230–233. doi:10.1126/science.1153201. Retrieved 2 November 2021.
  6. ^ "Academy of Europe: Wain-Hobson Simon". Retrieved 2021-06-07.
  7. ^ "No. 63571". The London Gazette (Supplement). 1 January 2022. p. N27.