Sirius Red
Appearance
Names | |
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IUPAC name
Hexasodium (3E)-4-oxo-7-[[(6E)-5-oxo-7-sulfonato-6-[[2-sulfonato-4-[(4-sulfonatophenyl)diazenyl]phenyl]hydrazinylidene]naphthalen-2-yl]carbamoylamino]-3-[[2-sulfonato-4-[(4-sulfonatophenyl)diazenyl]phenyl]hydrazinylidene]naphthalene-2-sulfonate
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Other names
Direct Red 80; Picrosirius Red
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Identifiers | |
3D model (JSmol)
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ECHA InfoCard | 100.018.208 |
PubChem CID
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CompTox Dashboard (EPA)
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Properties | |
C45H26N10Na6O21S6 | |
Molar mass | 1373.05 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Sirius Red F 3B (Direct Red 80) is a azo dye used principally in staining methods for collagen and amyloid with the molecular formula C45H26N10Na6O21S6.[1]
In histology, sirius red staining is used in various domains of diagnostic to observe fibrosis levels in a lot of cases of inflammation induced by cancer, vascular or metabolic pathologies.[2]
In bright field microscopy the following can be observed:
- The nuclei in yellow
- The cytoplasm in yellow
- Collagen fibers in red
- Muscular fibers in yellow
- Red blood cells in yellow
References
- ^ ResearchGate"Certification procedures for sirius red F3B". Retrieved 2015-08-21.
- ^ Sirius red