From Wikipedia, the free encyclopedia
  • 2-(2-Methoxy-4-methylsulfinylphenyl)-1H-imidazo[4,5-b]pyridine
CAS Number
PubChem CID
CompTox Dashboard (EPA)
ECHA InfoCard100.070.348 Edit this at Wikidata
Chemical and physical data
Molar mass287.34 g·mol−1
3D model (JSmol)
  • COC1=C(C=CC(=C1)S(=O)C)C2=NC3=C(N2)C=CC=N3

Sulmazole is a cardiotonic drug.[1] Sulmazole has the chemical formula C14H13N3O2S[2] and a molecular weight of 287.34 g/mol.[2]

Sulmazole has been shown to improve cardiac index and reduce pulmonary capillary wedge pressure without significant changes in a person's heart rate or arterial pressure.[3] Sulmazole inhibits the A1 adenosine receptor and functionally blocks Gi, an inhibitory regulator.[1] Sulmazole is also a phosphodiesterase inhibitor.[3] Sulmazole is classified as an imidazopyridine and a sulfoxide.[2] Sulmazole can be taken intravenously or orally.[3] Side effects from sulmazole include blurring vision and temporary color blindness.[3]


  1. ^ a b Parsons WJ, Ramkumar V, Stiles GL (April 1988). "The new cardiotonic agent sulmazole is an A1 adenosine receptor antagonist and functionally blocks the inhibitory regulator, Gi". Molecular Pharmacology. 33 (4): 441–8. PMID 3128727.
  2. ^ a b c PubChem. "Sulmazole". Retrieved 2019-09-30.
  3. ^ a b c d "NCATS Inxight: Drugs — SULMAZOLE". Retrieved 2019-09-30.