TB10Cs4H4 snoRNA

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Consensus structure of TB10Cs4H4

TB10Cs4H4 is a member of the H/ACA-like class of non-coding RNA (ncRNA) molecule that guide the sites of modification of uridines to pseudouridines of substrate RNAs. It is known as a small nucleolar RNA (snoRNA) thus named because of its cellular localization in the nucleolus of the eukaryotic cell. TB10Cs4H4 is predicted to guide the pseudouridylation of SSU ribosomal RNA (rRNA) at residue Ψ505.[1]


  1. ^ Liang, XH; Uliel, S; Hury, A; Barth, S; Doniger, T; Unger, R; Michaeli, S (May 2005). "A genome-wide analysis of C/D and H/ACA-like small nucleolar RNAs in Trypanosoma brucei reveals a trypanosome-specific pattern of rRNA modification.". RNA (New York, N.Y.). 11 (5): 619–45. PMC 1370750Freely accessible. PMID 15840815. doi:10.1261/rna.7174805.