TP53I3

TP53I3
Available structures
PDB	Human UniProt search: PDBe RCSB
List of PDB id codes
	2J8Z, 2OBY
Identifiers
Aliases	TP53I3, PIG3, tumor protein p53 inducible protein 3
External IDs	OMIM: 605171; HomoloGene: 36617; GeneCards: TP53I3; OMA:TP53I3 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	24,085,861 bp
RNA expression pattern
	Top expressed in
	mucosa of ileum; ; pancreatic ductal cell; ; mucosa of transverse colon; ; duodenum; ; rectum; ; body of pancreas; ; vagina; ; left testis; ; gallbladder; ; upper lobe of left lung;
	n/a
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	oxidoreductase activity; protein homodimerization activity; NADPH binding; quinone binding; NADPH:quinone reductase activity;
Cellular component	cytosol;
Biological process	NADP metabolic process; regulation of apoptotic process;
	Sources:Amigo / QuickGO
Orthologs
	9540
	n/a
	ENSG00000115129
	n/a
	Q53FA7
	n/a
	NM_001206802; NM_004881; NM_147184
	n/a
	NP_001193731; NP_004872; NP_671713
	n/a
	Wikidata
View/Edit Human

Putative quinone oxidoreductase is an enzyme that in humans is encoded by the TP53I3 gene.^[3]^[4]^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000115129 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Contente A, Dittmer A, Koch MC, Roth J, Dobbelstein M (Mar 2002). "A polymorphic microsatellite that mediates induction of PIG3 by p53". Nat Genet. 30 (3): 315–20. doi:10.1038/ng836. PMID 11919562.
^ Flatt PM, Polyak K, Tang LJ, Scatena CD, Westfall MD, Rubinstein LA, Yu J, Kinzler KW, Vogelstein B, Hill DE, Pietenpol JA (Jul 2000). "p53-dependent expression of PIG3 during proliferation, genotoxic stress, and reversible growth arrest". Cancer Lett. 156 (1): 63–72. doi:10.1016/S0304-3835(00)00441-9. PMID 10840161.
^ Porte S, Valencia E, Yakovtseva EA, Borras E, Shafqat N, Debreczeny JE, Pike AC, Oppermann U, Farres J, Fita I, Pares X (Jun 2009). "Three-dimensional structure and enzymatic function of proapoptotic human p53-inducible quinone oxidoreductase PIG3". J Biol Chem. 284 (25): 17194–205. doi:10.1074/jbc.M109.001800. PMC 2719357. PMID 19349281.{{cite journal}}: CS1 maint: unflagged free DOI (link)
^ "Entrez Gene: TP53I3 tumor protein p53 inducible protein 3".