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TSPY1

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(Redirected from TSPY1 (gene))
TSPY1
Identifiers
AliasesTSPY1, CT78, DYS14, TSPY, pJA923, testis specific protein, Y-linked 1, testis specific protein Y-linked 1
External IDsOMIM: 480100; HomoloGene: 87844; GeneCards: TSPY1; OMA:TSPY1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_003308
NM_001197242
NM_001320964

n/a

RefSeq (protein)

NP_001184171
NP_001307893
NP_003299

n/a

Location (UCSC)Chr Y: 9.47 – 9.47 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Testis-specific Y-encoded protein 1 is a protein that in humans is encoded by the TSPY1 gene.[3]

The protein encoded by this gene is found only in testicular tissue and may be involved in spermatogenesis. Approximately 35 copies of this gene are present in humans, but only a single, nonfunctional orthologous gene is found in mice. Two transcript variants encoding different isoforms have been found for this gene.[4] The protein is strongly overexpressed in gonadoblastoma.[5]

See also

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References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000258992Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ "Entrez Gene: TSPY1 Testis specific protein, Y-linked 1".
  4. ^ "TSPY1 testis specific protein Y-linked 1 [Homo sapiens (human)] - Gene - NCBI".
  5. ^ Schnieders F, Dörk T, Arnemann J, et al. (1997). "Testis-specific protein, Y-encoded (TSPY) expression in testicular tissues". Hum. Mol. Genet. 5 (11): 1801–7. doi:10.1093/hmg/5.11.1801. PMID 8923009.

Further reading

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