Talk:Five-prime cap

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SanderB 22:49, 4 January 2006 (UTC) still a stub???


I was about to ask the same thing! I doubt it at the moment, it covers the basics pretty well... -- Serephine talk - 13:37, 16 June 2006 (UTC)


The article says: "GMP is added to the terminal phosphates (by a guanylyl transferase), losing two phosphate groups (from the GMP) in the process.". I think it should say "GTP is added... losing two phosphates (from the GTP)...", because GMP is a monophosphate with one (not three) phosphate group. When GTP loses two phosphates, it becomes GMP, and then GMP is added. The GMP's phosphate and the 5' end's two phosphates create the 5'-5' triphosphate linking. This should be checked. Also, the positive charge at the methylated guanine should be mentioned--Miguelferig (talk) 19:00, 3 April 2013 (UTC)