Talk:NF1

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Wrong[edit]

You are literally just making randim stuff up Bruh you wrong (talk) 06:26, 2 September 2017 (UTC)[reply]

Changes[edit]

I plan on adding to this article for a project in my advance genetics class. Here is a basic outline of what I plan on adding

Structure of Article

Gene

- The NF1 gene encodes a tumour suppressor protein called neurofibromin (PMID: 27622733)

- Located on chromosome 17, band q 11.2

- Gene spans more than 280kb

- PMID: 26671924

Mutations

Structure

Function

- Protein involved in accelerating GTP hydrolysis on Ras proteins (PMID: 8563751)

- Plays a role in keratinocytes and melanocytes (PMID: 27622733)

- regulates melanin synthesis and keratinocyte differentiation (PMID: 27622733)

- role in tumorigenesis and cancer ( PMID: 27622733)

Related Conditions

- Neurofibromatosis