Tetrahydropapaveroline

From Wikipedia, the free encyclopedia
Jump to navigation Jump to search
Tetrahydropapaveroline
Tetrahydropapaveroline.svg
Names
IUPAC name
1-[(3,4-dihydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol
Other names
Norlaudanosoline; Tetrahydroxypapaveroline
Identifiers
3D model (JSmol)
ECHA InfoCard 100.158.898
Properties
C16H17NO4
Molar mass 287.315 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Tetrahydropapaveroline (norlaudanosoline) is a benzyltetrahydroisoquinoline alkaloid.[1]

It can be formed in trace amounts in the brain by a condensation reaction of dopamine and dopaldehyde (a metabolite of dopamine).[1][2]

It inhibits dopamine uptake within the cerebral cortex.[citation needed]

References[edit]

  1. ^ a b Richter, Derek. Addiction and Brain Damage. Routledge. p. 24. ISBN 9781315454030.
  2. ^ RD Myers, CL Melchior (29 Apr 1977). "Alcohol drinking: abnormal intake caused by tetrahydropapaveroline in brain". Science. 196 (4289): 554–556. doi:10.1126/science.557839.CS1 maint: Uses authors parameter (link)