Jump to content

Stanozolol

From Wikipedia, the free encyclopedia

This is an old revision of this page, as edited by SieBot (talk | contribs) at 16:35, 29 May 2007 (robot Adding: nl:Stanozolol). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

Stanozolol
Clinical data
Pregnancy
category
  • X
Routes of
administration
Oral, Intramuscular
ATC code
Legal status
Legal status
  • Prescription only
    (US)
Pharmacokinetic data
Bioavailability?
MetabolismHepatic
Elimination half-life1 day[1]
ExcretionRenal: 84%
Identifiers
  • 7β-Hydroxy-17-methyl-
    5α-androstano[3,2-c]pyrazole
CAS Number
PubChem CID
CompTox Dashboard (EPA)
ECHA InfoCard100.030.801 Edit this at Wikidata
Chemical and physical data
FormulaC21H32N2O
Molar mass328.49 g·mol−1

Stanozolol, commonly sold under the name Winstrol (oral) and Winstrol Depot (intra-muscular), was developed by Winthrop Laboratories in 1962. It is a synthetic anabolic steroid derived from testosterone, and has been approved by the FDA for human use.

Unlike most injectable anabolic steroids, Stanozolol is not esterified and is sold as an aqueous suspension, or in oral tablet form. The drug has a large oral bioavailability, due to a C17 α-alkylation which allows the hormone to survive first pass liver metabolism when ingested. It is because of this that Stanozolol is also sold in tablet form.

Stanozolol has been used on both animal and human patients for a number of conditions. In humans, it has been demonstrated to be successful in treating anaemia and hereditary angioedema. Veterinarians may prescribe the drug to improve muscle growth, red blood cell production, increase bone density and stimulate the appetite of debilitated or weakened animals.

Stanozolol is one of the Anabolic steroids commonly used as an ergogenic aid and is banned from use in sports competition under the auspices of the International Association of Athletics Federations (IAAF).

Use in bodybuilding

Like other anabolic steroids, stanolozol is classified as a Schedule III controlled substance under federal regulation. In New York, the state legislature classifies analbolic steroids under DEA Schedule II.

Used illegally in bodybuilding, typically "stacked" with other testosterone-based anabolic steroids, Stanozolol is liked by many due to the fact it causes strength increases without excess weight-gain, promotes increases in vascularity, and will not convert to estrogen.[2] It also does not cause excess water retention, and even sometimes is thought to have a diuretic effect on the body.

Stanozolol is commonly used by athletes and bodybuilders alike to lose fat while retaining lean body mass. It is usually used in a cutting cycle, to help preserve lean body mass while metabolizing adipose, although it has not been proven conclusively that it has any special fat-burning properties.

It is presented most commonly as a 50 mg/mL injection or a 50 mg tablet. However, recently 100 mg/mL versions have become available. A common dosage can be 25-100 mg/day, with optimal results usually seen at 50 mg/day. It is reduced to micrometer particles in aqueous suspension and does not have a typical elimination half-life. Authentic Stanozol can easily be seen, because it will separate in its container if left undisturbed for a number of hours (the micronized crystal will fall to the bottom, and the water suspension will rise to the top). It has a white, milky colour.

It should be taken no more than 48 hours apart, with some users preferring to inject every day, or even twice a day, to maintain serum levels.

The drug has been known to cause masculinising side-effects in women with doses as low as 2 mg per day, and liver damage has been known to occur with extended usage of larger doses.

An alternative to Stanzolol is Furazabol. Furazabol's effects are virtually identical to Stanzolol except that instead of having an extremely adverse effect on cholesterol values, Furazabol actually improves a person's blood lipid profile (at therapeutic doses, not performance enhancing ones).[citation needed] Sold under the trade name Mitolan, Furazabol is a standard treatment in Japan for hyperlipemia.

Publicised abuse cases

References