Theophilus Painter
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Theophilus Shickel Painter (August 22, 1889 – October 5, 1969) was an American zoologist best known for his work on the structure and function of chromosomes, especially the sex-determination genes X and Y in humans.[1] He was the first to discover that human sex was determined by an X/Y heteromorphic chromosomal pair mechanism.[2][3] He also carried out work in identifying genes in fruit flies (Drosophila). His work exploited the giant polytene chromosomes in the salivary glands of Drosophila and other Dipteran larvae.
Academic administration
Painter joined the faculty at the University of Texas in 1916 and, except for military duty during World War I, stayed there his whole career. He was, in succession, associate professor, professor and distinguished professor of zoology. He served as acting president (1944–1946) and president (1946–1952) of the University of Texas and retired from active teaching in 1966.
Racial segregation
Painter was president of the University of Texas when Texas resident Heman Marion Sweatt applied for and was denied admission due to his race. Subsequently, Painter was the named defendant in the civil rights case Sweatt v. Painter, 339 U.S.629 (1950), which proved an integral stepping stone in the landmark case Brown v. Board of Education of Topeka, Kansas that held that "separate is inherently unequal" and led to the integration of America's public schools.
Gender research
Painter is also known for his early study of human chromosomes. In 1921 he first gave the number 24 for the count of human meiotic chromosomes. He had tried to count the tangled mass of chromosomes he could see under a microscope in spermatocytes in slices of testicle and arrived at the figure of 24.[2] Others later repeated his experiment in other ways and agreed upon the number of 24. Popular thinking held that if there were 24 chromosomes in spermatocytes, there must be an equal number contributed by the female and the human chromosome number must be 48, which was undisputed for more than 30 years.[4] Then in 1955, Joe Hin Tjio, using more advanced techniques, looked at the chromosomes in human somatic cells and found 46 chromosomes. Together with Albert Levan, Tjio published his finding in early 1956, and the human chromosome number was finally revised.
In 1934 Painter was awarded the Daniel Giraud Elliot Medal from the National Academy of Sciences.[5]
See also
References
- ^ Entry on Painter by Dorothy Haskett in The Embryo Project Encyclopedia
- ^ a b Rudle, Frank H. (2004) "Theophilus Painter: First Steps Toward an Understanding of the Human Genome", J. Experimental Zoology, 301A, 375–377. Retrieved 24 Jan. 2022.
- ^ Glass, Bentley (1990) Theophilus Shickel Painter 1889—1969: A Biographical Memoir, National Academy of Sciences, Washington DC. Retrieved 24 Jan 2022.
- ^ Matthews, Robert. "The bizarre case of the chromosome that never was" (PDF). Archived from the original (PDF) on 15 December 2013. Retrieved 13 July 2013.
- ^ "Daniel Giraud Elliot Medal". National Academy of Sciences. Retrieved 16 February 2011.
External links
- Theophilus Shickel Painter from the Handbook of Texas Online
- Theophilus Painter — Biographical Memoirs of the National Academy of Sciences
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