Troxacitabine

Troxacitabine
Identifiers
	IUPAC name 4-amino-1-[(2S,4S)-2-(hydroxymethyl)-1,3-dioxolan-4-yl]pyrimidin-2(1H)-one;
CAS Number	145918-75-8 ;
PubChem CID	151173;
ChemSpider	399955 ;
UNII	60KQZ0388Y;
ChEMBL	ChEMBL359164 ;
CompTox Dashboard (EPA)	DTXSID2048791 ;
Chemical and physical data
Formula	C8H11N3O4
Molar mass	213.19 g/mol g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C1/N=C(/N)\C=C/N1[C@H]2O[C@H](OC2)CO;
	InChI InChI=1S/C8H11N3O4/c9-5-1-2-11(8(13)10-5)6-4-14-7(3-12)15-6/h1-2,6-7,12H,3-4H2,(H2,9,10,13)/t6-,7-/m0/s1 ; Key:RXRGZNYSEHTMHC-BQBZGAKWSA-N ;
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Troxacitabine (brand name Troxatyl) is a nucleoside analogue with anticancer activity. Its use is being studied in patients with refractory lymphoproliferative diseases.^[1]

References

^ Vose, Julie M.; Panwalkar, Amit; Belanger, Robert; Coiffier, Bertrand; Baccarani, Michele; Gregory, Stephanie A.; Facon, Thierry; Fanin, Renato; Caballero, Dolores; Ben-Yehuda, Dina; Giles, Francis (2007). "A phase II multicenter study of troxacitabine in relapsed or refractory lymphoproliferative neoplasms or multiple myeloma". Leukemia & Lymphoma. 48 (1): 39–45. doi:10.1080/10428190600909578.

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