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Uremic frost

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Example of uremic frost.

Uremic frost is a colloquial description for crystallized urea deposits that can be found on the skin of those affected by Chronic kidney disease. In states of prolonged kidney failure and subsequent uremia, the high level of urea in the bloodstream leads to high levels of urea secreted by eccrine sweat glands as a component of sweat. As water evaporates off of the skin, it results in crystallization of the remaining urea.

This condition is more common in severe, untreated uremia and is associated with serum BUN levels >200. It becoming rare in people with chronic kidney disease managed on long-term hemodialysis, with estimated prevalence between 0.8 to 3%.[1][2][3]

References

  1. ^ Lynde, Carrie; Kraft, John. "Skin manifestations of kidney disease". Parkhurst Exchange. Retrieved 2 October 2014.
  2. ^ Falodun O, Ogunbiyi A, Salako B, George AK (2011). "Skin changes in patients with chronic renal failure". Saudi J Kidney Dis Transpl. 22 (2): 268–72. PMID 21422624. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)
  3. ^ Udayakumar P, Balasubramanian S, Ramalingam KS, Lakshmi C, Srinivas CR, Mathew AC (2006). "Cutaneous manifestations in patients with chronic renal failure on hemodialysis". Indian J Dermatol Venereol Leprol. 72 (2): 119–25. PMID 16707817.{{cite journal}}: CS1 maint: multiple names: authors list (link)