Urtoxazumab
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| Monoclonal antibody | |
|---|---|
| Type | Whole antibody |
| Source | Humanized (from mouse) |
| Target | E. coli Shiga-like toxin II B subunit |
| Clinical data | |
| ATC code |
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| Identifiers | |
| CAS Number | |
| ChemSpider |
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| Chemical and physical data | |
| Formula | C6414H9934N1718O2010S40 |
| Molar mass | 144.6 kg/mol g·mol−1 |
  (what is this?) (verify) | |
Urtoxazumab is a humanized monoclonal antibody against diarrhoea caused by Escherichia coli, serotype O121. The drug is designed to bind to a toxin of this bacterium, so that it can be more easily broken down and eliminated from the body.[1][2]
References[edit]
- ^ International Nonproprietary Names for Pharmaceutical Substances (INN), World Health Organization.
- ^ López, EL; Contrini, MM; Glatstein, E; González Ayala, S; Santoro, R; Allende, D; Ezcurra, G; Teplitz, E; et al. (2009). "Safety and Pharmacokinetics of Urtoxazumab, a Humanized Monoclonal Antibody Against Shiga-Like Toxin 2 in Healthy Adults and Pediatric STEC- Infected Patients". Antimicrobial Agents and Chemotherapy. 54 (1): 239–243. doi:10.1128/AAC.00343-09. PMC 2798559. PMID 19822704.
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