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Would it be beneficial to add in Synaptopathy a section about cochlear synaptopathy? I have found multiple references to it.

I also want to add a table or figure to this article. To whoever is reviewing this, what ideas do you have?

I will be adding summaries to these references over the next few days.

Here are three recent review articles: [4] [5] [6]

Here is an additional primary source: [7]

Biophysics Editor (talk) 15:11, 26 October 2017 (UTC)

Peer review by Jarett Anderson- Your sources are great, I would suggest as your next step to show how you plan to implement your research into the original article. I would copy and paste the paragraphs where you plan to add your research, or to specify that you may be making entirely new paragraphs. Once you have done that, simply make a rough outline or summary of what you wish to incorporate into that article. Good luck!

Updated Article:

A common cause of synaptopathy is glutamate excitotoxicity. As shown in the animation, the over activation of NMDA receptors leads to an increase in free intracellular calcium, which produces oxygen free-radicals and eventually neuronal dysfunction.

Another example of synaptopathy occurs in the auditory system. This cochlear synaptopathy has been seen after prolonged noise exposure in both primate and non-primate models. [1] [2] Two possible reasons for this neuronal death are both glutamate-mediated excitotoxicity in the postsynaptic terminal, and presynaptic ribbon damage which occurs by an unknown mechanism. [3]

Peer review by Jarett Anderson

Based on your presentation, I think this image is awesome! Did you get it off of Wikimedia, or do you have all the copyright work done to be able to post this to Wikipedia tomorrow? I would explain what the image is portraying in both the caption of the image as well as the paragraph beginning with "Another example of synaptopathy occurs in the auditory system...". Great progress, excited to see the final product!

Jarett

I got it off of Wikimedia. Thanks for the input. I'll be sure and captions in both the paragraph and under the image. Thanks! Caden