User:Bthomp34/sandbox
Wendy Chung | |
|---|---|
| Born | |
| Nationality | American |
| Alma mater | Rockefeller University, Cornell University |
| Occupation(s) | Clinical and molecular geneticist, physician |
Wendy Chung is an American clinical and molecular geneticist and physician.[1] She currently directs the clinical genetics program at Columbia University[2] and serves as the Kennedy Family Professor of Pediatrics.[3][4] She is the author of 300 peer-reviewed articles and 50 chapters[5] and has won several awards as a physician, researcher, and professor.[6] Chung helped to initiate a new form of newborn screening for spinal muscular atrophy which is used nationally, and was the plaintiff in the supreme court case which prevents patenting of genes.[7]
Her research "relates to the molecular genetics of obesity and diabetes in rodents and humans, the genetic basis of congenital heart disease, cardiomyopathies, arrhythmias, long QT Syndrome, pulmonary hypertension, endocrinopathies, congenital diaphragmatic hernias, cleft lip/cleft palate, seizures, mental retardation, inherited metabolic conditions and breast and pancreatic cancer susceptibility."[4]
Early life and education
[edit]Chung was born in Nebraska and raised in southern Florida.[8] Her parents were involved in science and medicine: her father was an organic chemistry professor and her mother worked in a medical laboratory.[3] She was the first Miami-Dade County public high school student to win the Westinghouse Science Talent Search, the predecessor to the Regeneron Science Talent Search.[8] In high school, Chung was valedictorian and a National Merit Scholar.[3][9]
Chung earned a bachelor's degree in biochemistry and economics at Cornell University, graduating in 1990.[4] She earned a Ph.D. in genetics from Rockefeller University in 1996 and a M.D. from Cornell University Medical College in 1998.[10][4] She was a graduate student of Dr. Rudy Leibel at Rockefeller, who described her as a "triple threat" due to her capability as an "equally gifted scientist, clinician, and teacher."[8] Chung also completed an internship, residency, and fellowship at the New York-Presbyterian Hospital, Columbia University Medical Center.[11] Both her internship and residency were focused in pediatrics, while her two fellowships were focused in Molecular Genetics and Clinical Genetics.[3]
Career
[edit]Chung directs the Pediatric Heart Network Genetic Core, the Pediatric Neuromuscular Network Molecular Core, the New York Obesity Center Molecular Genetics Core and the Diabetes and Endocrine Research Center Molecular Genetics Core, among her positions.[4] She holds board certifications in Clinical Genetics and Genomics (MD).
Chung's areas of expertise include neurodevelopment disorders, autism, clinical genetics, developmental disorder, precision medicine, birth defects, breast cancer, cancer genetics, cardiomyopathy, cleft palate with cleft lip, congenital diaphragmatic hernia, congenital heart disease, diabetes, genetic counseling, inborn metabolism disorder, inherited arrhythmias, neurogenetics, obesity, pancreatic cancer, pediatric seizures, pulmonary hypertension, rare cancer syndromes, arrhythmia, seizures, and spinal muscular atrophy.[12]
Chung was named one of New York Magazine's "best doctors" and one of America's "top doctors" by Castle Connolly Medical Ltd. in a survey conducted when more than 250,000 "leading doctors" were asked to "name America's best physicians in various specialties."[13]
Supreme Court Case Involvement
[edit]Chung was an original plaintiff in the Supreme Court case which overturned that ability to patent genes, Association for Molecular Pathology v. Myriad Genetics, Inc.[14]. Chung became a plaintiff with the ACLU after approaching both the NIH and Congress as she believed that the patenting of genes restricted access and quality of care the patients are eligible to receive.[15][16] The court sided with the Association for Molecular Pathology unanimously, and determined that as genes are natural, they are not able to be patented.[15] Chung believes that these decisions will allow patients to receive all the information resulting from genome sequencing, and allowing testing for specific diseases - such as the test for breast cancer - thus enabling patients to know more about their own health.[15]
Positions
[edit]Chung directs the Pediatric Heart Network Genetic Core, the Pediatric Neuromuscular Network Molecular Core, the New York Obesity Center Molecular Genetics Core and the Diabetes and Endocrine Research Center Molecular Genetics Core, among her positions at Columbia University and the Simons Foundation.[4]
Columbia University
[edit]Chung is a Kennedy Family Professor of Pediatrics at Columbia University and directs their clinical genetics program [4][10]. She has also received the Presidential Award for Outstanding Teaching from Columbia in recognition of her teaching and mentoring of students [10]. Chung also directs the fellowship program in Cytogenetics and Molecular Genetics at Columbia University, supervises medical education in human genetics at Columbia University Medical School, and is the director of the Clinical Cancer Genetics program and the DISCOVER program.[4][17]
Chung directs clinical research at the Simons Foundation Autism Research Initiative and leads both the Simons Foundation Powering Research through Knowledge (SPARK); which is seeking to create a group of 50,000 individuals with Autism who are to contribute data in the form of saliva, medical, and behavioral information[18], and the Simons Variation in Individuals Project (Simons VIP), in which individuals with a variation in a specific segment of their genetic makeup that increases their risk of autism are identified and studied through various tests and neuroimaging to identify new profiles which may be shared by these individuals [19]. In these endeavors, Chung works to manage research programs, evaluate new treatments and medications, and develop novel outcome measures for evaluation of the new treatments.Furthermore, she seeks to identify gene associations with autism and the specific clinical features which may characterize particular gene associations. Alongside her research endeavors, Chung works with the families involved in the project to create community and help them to understand autism and its causes more completely.[20]
Research Contributions
[edit]Throughout her career, Chung's research largely to the genetic basis of human diseases, specifically learning the discovery of new genes and mutations associated with diseases, then implementing these revelations into clinical treatments.[21] Throughout her career, Chung has discovered 25 new genes that cause human diseases.[12]
Obesity and Diabetes
[edit]Chung worked primarily in research related to the influence of genetic variation in susceptibility to obesity and diabetes, using rodent genetic models as a foundation from which to expand research to humans.[21] In this research, Chung was able to clone a rodent gene designed to prevent obesity and regulate body weight.[21] Her later work expands to human obesity and diabetes susceptibility and prevention.[21]
Inborn Errors of Metabolism
[edit]Working with less common disorders, Chung has researched mutations and disease associations with Wolfram syndrome, Wolman disease, Leigh syndrome, glycogen storage disease type 111, and juvenile idiopathic arthritis.[21]
Birth Defects
[edit]Chung's research on birth defects focuses on determining the genetic basis of birth defects, focusing predominately on congenital diaphragmatic hernia (CDH) and congenital heard disease[21]. Her studies on CDH have been published in Nature and Science, and have results showing mutations to be rare causes of CDH [21].
Cardiac Disease
[edit]Chung has concentrated research efforts for cardiac disease on pulmonary arterial hypertension, inherited arrhythmias, and cardiomyopathies [21].
Chung maintains the North American Hereditary Pulmonary Hypertension Registry, an has found four genes which may cause pulmonary hypertension[21]. Chung's current research is focused on identifying genes leading to pulmonary hypertension in children[21].
Chung's work researching Cardiomyopathies describes metabolic causes, identify genetic modifiers of disease progression in children and infants with the hypertrophic cardiomyopathy and novel genes for infantile cardiomyopathy.[21]
Spinal Muscular Atrophy
[edit]One of Chung's contributions within the field of genetics involves her role in the development of screenings and treatment for spinal muscular atrophy (SMA),especially in newborns.Chung worked as a part of a team to develop a new screening and intervention process for infants with spinal muscular atrophy, with a pilot study conducted with a population of infants in New York identifying and successfully treating one infant with SMA.[22]
Chung has also conducted a natural history study to understand how spinal muscular atrophy progresses to provide a foundation for clinical trials[21].
Cancer
[edit]Chung focuses on a variety of cancer types, including breast cancers and pancreatic cancers, along with several rare forms of cancer and the clinical implementation of testing for cancers.
In her research focused on breast cancer, Chung works at the New York location of the Breast Cancer Family Registry, studying predominately heritable breast cancers [21]. Genetic research in this area has been largely centered on variations of the BRCA1/BRCA2 mutations, as well as how genetics affect decision, health behaviors, and outcomes for patients[21].
Chung's research within the Columbia pancreas cancer genetic program discovered 27% of patients from the program had identifiable genetic causes for their pancreatic cancer[21].
Autism and Neurodevelopmental Disorders
[edit]Chung's research on neurodevelopment disorders at Columbia has resulted in the identification of novel genes associated with neurodevelopment disabilities and autism, including KAT6A, PPP2R5D, PRUNE, EMC1, AHDC1, POGZ, PURA, ARID2, DDX3X, SETD2, and SPATA5 [21].
In April 2014, Chung spoke at TED2014, delivering a talk called "Autism - What we know (and what we don't know yet)."[23][24] Chung discussed different ways in which genetics and autism interact, with some individuals with autism resulting from a single genetic factor, and other individuals with multifactorial autism, caused by multiple factors and genes.[25] Additionally, Chung touched on the ameliorable effects of early detection of autism, along with new testing practices such as eye tracking test for babies which detects whether they have difficulty maintaining eye contact.[25]
Papers
[edit]| Topic | Article Title |
|---|---|
| Congenital Heart Disease | Contribution of rare inherited and de novo variants in 2,871 congenital heart disease probands[26] |
| De novo mutations in congenital heart disease with neurodevelopmental and other congenital anomalies[27] | |
| Increased Frequency of De novo Copy Number Variations in Congenital Heart Disease by Integrative Analysis of SNP Array and Exome Sequence Data [28] | |
| De novo mutations in histone-modifying genes in congenital heart disease[29] | |
| Congenital Diaphragmatic Hernia | Increased burden of de novo predicted deleterious variants in complex congenital diaphragmatic hernia[30] |
| Whole exome sequencing identifies de novo mutations in GATA6 associated with congenital diaphragmatic hernia[31] | |
| Variants in GATA4 are a rare cause of familial and sporadic congenital diaphragmatic hernia[32] | |
| Pulmonary Hypertension | Whole Exome Sequencing to Identify a Novel Gene (Caveolin-1) Associated With Human Pulmonary Arterial Hypertension[33] |
| Spinal Muscular Atrophy | Pilot study of population-based newborn screening for spinal muscular atrophy in New York state[22] |
| Spectrum of Neuropathophysiology in Spinal Muscular Atrophy Type I[34] | |
| The motor neuron response to SMN1 deficiency in spinal muscular atrophy[35] | |
| Autism and Neurogenetics | Autism Spectrum Disorder, Developmental and Psychiatric Features in 16p11.2 Duplication [36] |
| De novo missense variants in PPP2R5D are associated with intellectual disability, macrocephaly, hypotonia, and autism[37] | |
| Mutations in TKT Are the Cause of a Syndrome Including Short Stature, Developmental Delay, and Congenital Heart Defects[38] | |
| Progress in Understanding and Treating SCN2A-Mediated Disorders[39] | |
| Quantifying the Effects of 16p11.2 Copy Number Variants on Brain Structure: A Multisite Genetic-First Study[40] | |
| De novo and inherited mutations in the X-linked gene CLCN4 are associated with syndromic intellectual disability and behavior and seizure disorders in males and females[41] | |
| Mutations in SPATA5 Are Associated with Microcephaly, Intellectual Disability, Seizures, and Hearing Loss[42] | |
| A Recurrent PDGFRB Mutation Causes Familial Infantile Myofibromatosis[43] |
| 2018 | New York Academy Medal for Distinguished Contributions in Biomedical Science[5][7] |
| 2017 | Best Grand Rounds of the Year, Department of Pediatrics Columbia University |
| 2015 | American Society for Clinical Investigation |
| 2014 | Samberg Scholars in Children’s Health |
| 2014 | Science Unbound Foundation’s Best Paper in 2013, PMID 23616257. |
| 2014 | Dean’s Distinguished Lecture in the Clinical Sciences |
| 2012-2017 | Castle Connolly's Top Doctors |
| 2012 | Member, Virginia Apgar Academy of Educators |
| 2012 | Inductee, Dade County Hall of Fame |
| 2011 | Distinguished Lecturer of the Year, Class of 2014, Columbia University |
| 2010 | Society of Pediatric Research, member |
| 2010 | Distinguished Lecturer of the Year, Class of 2013, Columbia University |
| 2009 | Presidential Award for Outstanding Teaching, Columbia University |
| 2008 | Medical Achievement Award, Bonei Olam |
| 2008 | Distinguished Lecturer, Class of 2011 |
| 2008 | Glenda Garvey Teaching Academy, member |
| 2005 | American Medical Women’s Association Mentor Award |
| 2005 | Best Translational Research, Columbia University Department of Pediatrics Assistant Professor Research Symposium |
| 2001 | Young Investigator Research Grant Award, American Academy of Pediatrics |
| 1998 | Dean’s Research Award, Cornell University Medical College |
| 1995 | Dean's Research Award, Cornell University Medical College |
| 1994 | Louis Gibofsky Memorial Prize, Cornell University Medical College |
| 1992 | American Institute of Nutrition, Outstanding Student Research Award |
Personal life
[edit]She has two sons[8] and spends most of her free time with her family, engaging in hiking, swimming, biking, solving puzzles, and going on scavenger hunts.[3]
References
[edit]- ^ "ASHG Panel Discusses Implementation of Clinical Sequencing in US, Europe". GenomeWeb. Retrieved 2016-05-01.
- ^ "Too Much Information". MIT Technology Review. Retrieved 2016-05-01.
- ^ a b c d e "309: Dr. Wendy Chung: Hunting Down Genes that Cause Human Disease". People Behind the Science Podcast. 2015-09-11. Retrieved 2016-05-01.
- ^ a b c d e f g h "Faculty and Staff | Institute of Human Nutrition". www.cumc.columbia.edu. Retrieved 2016-05-01.
- ^ a b "Columbia University Medical Center - The DHREAMS Team - Molecular Genetic Analysis of Congenital Diaphragmatic Hernia CDH". www.cdhgenetics.com. Retrieved 2016-05-01.
- ^ "Role of genetics in autism focus of free Kaiser lecture in Portland". OregonLive.com. Retrieved 2016-05-01.
- ^ a b "Wendy K. Chung, MD, PhD | Columbia University Department of Surgery". columbiasurgery.org. Retrieved 2018-10-17.
- ^ a b c d "Wendy Chung, MD, PhD | Naomi Berrie Diabetes Center". www.nbdiabetes.org. Retrieved 2016-05-01.
- ^ "2012 Miami-Dade County Public Schools Alumni Hall of Fame". www.engagemiamidade.net. Retrieved 2017-01-05.
- ^ a b c "Wendy K. Chung, MD, PhD". Institute of Human Nutrition. 2018-01-24. Retrieved 2018-12-08.
- ^ a b "Wendy K. Chung, MD, PhD | Columbia University Department of Surgery". columbiasurgery.org. Retrieved 2018-12-08.
- ^ a b "Wendy K. Chung, MD, PhD". Institute of Genomic Medicine. Retrieved 2018-12-11.
- ^ "Wendy K. Chung, MD, PhD- NewYork-Presbyterian". www.nyp.org. Retrieved 2016-05-01.
- ^ "Wendy K. Chung, MD, PhD | Columbia University Department of Surgery". columbiasurgery.org. Retrieved 2018-11-30.
- ^ a b c "Supreme Court Rules Against Gene Patents". Columbia University Irving Medical Center. 2013-06-14. Retrieved 2018-11-30.
- ^ "BRCA - Plaintiff Statements". American Civil Liberties Union. Retrieved 2018-11-30.
- ^ "Chung Lab at Columbia". Chung Lab at Columbia. Retrieved 2018-12-08.
- ^ "SPARK". SFARI. 2016-02-16. Retrieved 2018-12-08.
- ^ "Simons Variation in Individuals Project (Simons VIP)". SFARI. 2011-09-16. Retrieved 2018-12-08.
- ^ "Wendy Chung". SFARI. 2017-07-21. Retrieved 2018-12-08.
- ^ a b c d e f g h i j k l m n o p "Research". Chung Lab at Columbia. 2016-01-20. Retrieved 2018-12-11.
- ^ a b Chung, Wendy K.; Caggana, Michele; Vivo, Darryl C. De; LaMarca, Nicole M.; Young, Sally Dunaway; Andrew, Sarah P.; Jain, Ritu; Cohen, Lilian L.; Albertorio, Anthony (2018-06). "Pilot study of population-based newborn screening for spinal muscular atrophy in New York state". Genetics in Medicine. 20 (6): 608–613. doi:10.1038/gim.2017.152. ISSN 1530-0366.
{{cite journal}}: Check date values in:|date=(help) - ^ Chung, Wendy. "Wendy Chung | Speaker | TED.com". www.ted.com. Retrieved 2016-05-01.
- ^ Staff, NPR/TED. "Wendy Chung: Could Genetics Hold The Answer To Curing Autism?". NPR.org. Retrieved 2016-05-01.
- ^ a b "What we know about autism: Wendy Chung at TED2014". TED Blog. 2014-03-20. Retrieved 2018-12-11.
- ^ Brueckner, Martina; Lifton, Richard P.; Seidman, Christine E.; Gelb, Bruce D.; Seidman, Jonathan G.; Chung, Wendy K.; Goldmuntz, Elizabeth; Kaltman, Jonathan R.; Zhao, Hongyu (2017-11). "Contribution of rare inherited and de novo variants in 2,871 congenital heart disease probands". Nature Genetics. 49 (11): 1593–1601. doi:10.1038/ng.3970. ISSN 1546-1718.
{{cite journal}}: Check date values in:|date=(help) - ^ Chung, Wendy K.; Seidman, Christine E.; Lifton, Richard P.; Goldmuntz, Elizabeth; Gelb, Bruce D.; Brueckner, Martina; Seidman, Jonathan G.; Kaltman, Jonathan R.; Sanders, Stephan J. (2015-12-04). "De novo mutations in congenital heart disease with neurodevelopmental and other congenital anomalies". Science. 350 (6265): 1262–1266. doi:10.1126/science.aac9396. ISSN 1095-9203. PMID 26785492.
- ^ "Papers". Chung Lab at Columbia. 2015-12-08. Retrieved 2018-12-11.
- ^ Lifton, Richard P.; Seidman, Christine E.; Goldmuntz, Elizabeth; Gelb, Bruce D.; Chung, Wendy K.; Brueckner, Martina; Seidman, Jonathan G.; Zhao, Hongyu; Williams, Ismee A. (2013-06). "De novo mutations in histone-modifying genes in congenital heart disease". Nature. 498 (7453): 220–223. doi:10.1038/nature12141. ISSN 1476-4687.
{{cite journal}}: Check date values in:|date=(help) - ^ Chung, Wendy K.; Shen, Yufeng; Mychaliska, George B.; Azarow, Kenneth S.; Potoka, Douglas; Arkovitz, Marc S.; Stolar, Charles J.; Aspelund, Gudrun; Wynn, Julia (2015-08-15). "Increased burden of de novo predicted deleterious variants in complex congenital diaphragmatic hernia". Human Molecular Genetics. 24 (16): 4764–4773. doi:10.1093/hmg/ddv196. ISSN 0964-6906.
- ^ Chung, Wendy K.; Mefford, Heather; Genomics, University of Washington Center for Mendelian; Arkovitz, Marc S.; Aspelund, Gudrun; Stolar, Charles; Pietsch, John; Lim, Foong-Yen; Bucher, Brian (2014-03-01). "Whole exome sequencing identifies de novo mutations in GATA6 associated with congenital diaphragmatic hernia". Journal of Medical Genetics. 51 (3): 197–202. doi:10.1136/jmedgenet-2013-101989. ISSN 1468-6244. PMID 24385578.
- ^ Chung, Wendy K.; Arkovitz, Marc S.; Aspelund, Gudrun; Stolar, Charles; Bucher, Brian; Warner, Brad W.; Potoka, Douglas; Chung, Dai H.; Lim, Foong Yen (2013-03-01). "Variants in GATA4 are a rare cause of familial and sporadic congenital diaphragmatic hernia". Human Genetics. 132 (3): 285–292. doi:10.1007/s00439-012-1249-0. ISSN 1432-1203.
- ^ Austin Eric D.; Ma Lijiang; LeDuc Charles; Berman Rosenzweig Erika; Borczuk Alain; Phillips John A.; Palomero Teresa; Sumazin Pavel; Kim Hyunjae R. (2012-06-01). "Whole Exome Sequencing to Identify a Novel Gene (Caveolin-1) Associated With Human Pulmonary Arterial Hypertension". Circulation: Cardiovascular Genetics. 5 (3): 336–343. doi:10.1161/CIRCGENETICS.111.961888. PMC 3380156. PMID 22474227.
{{cite journal}}: CS1 maint: PMC format (link) - ^ Harding, Brian N.; Kariya, Shingo; Monani, Umrao R.; Chung, Wendy K.; Benton, Maryjane; Yum, Sabrina W.; Tennekoon, Gihan; Finkel, Richard S. (2015-1). "Spectrum of Neuropathophysiology in Spinal Muscular Atrophy Type I". Journal of neuropathology and experimental neurology. 74 (1): 15–24. doi:10.1097/NEN.0000000000000144. ISSN 0022-3069. PMC 4350580. PMID 25470343.
{{cite journal}}: Check date values in:|date=(help)CS1 maint: PMC format (link) - ^ Kang, Peter B.; Gooch, Clifton L.; McDermott, Michael P.; Darras, Basil T.; Finkel, Richard S.; Yang, Michele L.; Sproule, Douglas M.; Chung, Wendy K.; Kaufmann, Petra (2014-5). "The motor neuron response to SMN1 deficiency in spinal muscular atrophy". Muscle & nerve. 49 (5): 636–644. doi:10.1002/mus.23967. ISSN 0148-639X. PMC 4090017. PMID 23893312.
{{cite journal}}: Check date values in:|date=(help)CS1 maint: PMC format (link) - ^ Consortium, on behalf of the Simons VIP; Hanson, Ellen; Chung, Wendy K.; Spiro, John E.; Ledbetter, David H.; Martin, Christa L.; Sherr, Elliot; Roberts, Timothy; Kuschner, Emily (2016-08-01). "Autism Spectrum Disorder, Developmental and Psychiatric Features in 16p11.2 Duplication". Journal of Autism and Developmental Disorders. 46 (8): 2734–2748. doi:10.1007/s10803-016-2807-4. ISSN 1573-3432.
- ^ Chung, Wendy K.; Monaghan, Kristin G.; Retterer, Kyle; Folk, Leandra; Pearson, Margaret; Asaikar, Shailesh; Wu, Yvonne W.; Schuette, Jane; Innis, Jeffrey (2016-01-01). "De novo missense variants in PPP2R5D are associated with intellectual disability, macrocephaly, hypotonia, and autism". neurogenetics. 17 (1): 43–49. doi:10.1007/s10048-015-0466-9. ISSN 1364-6753. PMC 4765493. PMID 26576547.
{{cite journal}}: CS1 maint: PMC format (link) - ^ "Mutations in TKT Are the Cause of a Syndrome Including Short Stature, Developmental Delay, and Congenital Heart Defects". The American Journal of Human Genetics. 98 (6): 1235–1242. 2016-06-02. doi:10.1016/j.ajhg.2016.03.030. ISSN 0002-9297.
- ^ "Progress in Understanding and Treating SCN2A-Mediated Disorders". Trends in Neurosciences. 41 (7): 442–456. 2018-07-01. doi:10.1016/j.tins.2018.03.011. ISSN 0166-2236.
- ^ "Quantifying the Effects of 16p11.2 Copy Number Variants on Brain Structure: A Multisite Genetic-First Study". Biological Psychiatry. 84 (4): 253–264. 2018-08-15. doi:10.1016/j.biopsych.2018.02.1176. ISSN 0006-3223.
- ^ Kalscheuer, V. M.; Field, M.; Gecz, J.; Jentsch, T. J.; Stankiewicz, P.; Rosenfeld, J. A.; Niu, Z.; Lodh, S. P.; Shaw, M. (2018-02). "De novo and inherited mutations in the X-linked gene CLCN4 are associated with syndromic intellectual disability and behavior and seizure disorders in males and females". Molecular Psychiatry. 23 (2): 222–230. doi:10.1038/mp.2016.135. ISSN 1476-5578.
{{cite journal}}: Check date values in:|date=(help) - ^ "Mutations in SPATA5 Are Associated with Microcephaly, Intellectual Disability, Seizures, and Hearing Loss". The American Journal of Human Genetics. 97 (3): 457–464. 2015-09-03. doi:10.1016/j.ajhg.2015.07.014. ISSN 0002-9297.
- ^ "A Recurrent PDGFRB Mutation Causes Familial Infantile Myofibromatosis". The American Journal of Human Genetics. 92 (6): 996–1000. 2013-06-06. doi:10.1016/j.ajhg.2013.04.026. ISSN 0002-9297.
Category:Living people Category:American geneticists Category:American women scientists Category:Scientists from Florida Category:Cornell University alumni Category:Rockefeller University alumni Category:Cornell University faculty Category:American pediatricians Category:American people of Asian descent
Need 2,235 words minimum to meet requirements
Potential Article Topics for Project
Wendy Chung is a clinical and molecular geneticist and the Kennedy Family Professor of Pediatrics and Medicine. She helped to initiate a new form of newborn screening for spinal muscular atrophy which is used nationally, and was the plaintiff in the supreme court case which prevents patenting of genes. As an Asian American woman in science, she meets the qualifications for this topic as a member of an oppressed group operating as a renowned professional in a STEM field. Currently, her article on Wikipedia is very short given her prolific accomplishments, with few resources and no discussion on her talk page. This article would be expanded five-fold to meet the project requirements.
This source discusses Dr. Chung’s various awards, her role within Columbia University, and her areas of expertise.
http://columbiasurgery.org/wendy-k-chung-md-phd
This source is derived from one of her articles discussing her work on disorders and syndromes based upon deletions, providing accurate first hand information about one of her significant research projects.
Burnside, Rachel D., et al. "Features of Feingold syndrome 1 dominate in subjects with 2p deletions including MYCN." American Journal of Medical Genetics Part A, vol. 176, no. 9, 2018, p. 1956+. Academic OneFile, http://link.galegroup.com/apps/doc/A555222962/AONE?u=calpolyw_csu&sid=AONE&xid=8456008b. Accessed 10 Oct. 2018.
Carrie Derick was a botanist and geneticist living from 1862 – 1941, and became the first female professor in Canada. Despite her accomplishments and her work to fight discrimination on the basis of her gender, such as pushing to get a promotion to a professor position despite her university offering her lower-ranked positions, her article on Wikipedia remains a stub, which would need to be expanded five-fold. It is rated at stub-class, and is considered a high-importance article for the Wikiproject on Women Scientists.
This source comes from the Canadian government, summarizing her life and achievements as a historical figure.
https://www.collectionscanada.gc.ca/women/030001-1403-e.html
Mary F. Lyon was an English geneticist who lived from 1925 – 2014, and who is best known for her work on the inactivation of the x-chromosome. As a woman scientist who was a pioneer in her field, she meets the topic qualifications for the project. Furthermore, her article is rated as start-class with mid-importance and no information on her talk-page. This artlce would need to be expanded five-fold to meet the scope of work for this project.
This source from the US National Library of Medicine discusses her contributions on random X chromosome inactivation, and its links to human disorders.
https://www.ncbi.nlm.nih.gov/pubmed/21643983
Evaluation of Attachment in adults
The article "Attachment in adults" contains many basic elements of attachment theory in adults; however the explanation was rather unclear and the citations provided were not adequate for the information supplied throughout the article. The lead section was rather limited, providing a short and uninformative introduction to the topic without providing much, if any, information on attachment theory itself. Furthermore, when research was referred to throughout the article, sources were either omitted entirely or inaccurate, stating that studies provided information when only one study or no actual studies had been cited. This was especially evident in the discussion surrounding various types of attachment styles as well as the shared themes in research regarding the characteristics of adult attachment theory. In addition, many areas were rather repetitive, as with the section on the organization of working models, and others were somewhat irrelevant, such as the section on relationship dynamics, which would have been more useful when grouped with particular attachment styles rather than isolated from the attachment styles with which they interact. While the information was not overtly persuasive or biased, there was no reference to the critics surrounding attachment theory in adults or contrasting research, which may suggest different outcomes for individuals with secure and/or insecure attachments in early childhood. Overall, this article was comprehensible and provided foundational information on attachment theory applied to adult relationships, but needs improvement regarding organization, content quality, and both the quality and quantity of citations to validate the information provided.
 | This is a user sandbox of Bthomp34. You can use it for testing or practicing edits. This is not the sandbox where you should draft your assigned article for a dashboard.wikiedu.org course. To find the right sandbox for your assignment, visit your Dashboard course page and follow the Sandbox Draft link for your assigned article in the My Articles section. |