User:Chantestuser/sandbox/ArthurBrown
Arthur M “Buzz” Brown | |
|---|---|
 ChanTest's CEO Buzz Brown | |
| Occupation(s) | Founder, CEO, CSO |
Arthur M. “Buzz” Brown, M.D., Ph.D. is ChanTest’s founder, Executive Chairman & CSO, and an Adjunct Professor of Physiology and Biophysics at Case Western Reserve University, School of Medicine.
He is a trained cardiologist and physiologist with more than 30 years of experience in ion channels and their relationship to human disease and has published extensively in peer-reviewed journals.
Dr. Brown has established world-leading Physiology department at University of Texas Medical Branch, Baylor College of Medicine and Case Western Reserve University.
Early Life and education[edit]
Early career[edit]
Career[edit]
ChanTest[edit]
ChanTest company information needed here
ChanRX[edit]
ChanRX company information needed here
Honors and contributions[edit]
Dr. Brown’s honors include the following:
- Recipient of the prestigious Distinguished Service Award by the Safety Pharmacology Society (SPS) in 2013 [1]
- Established Investigator of the American Heart Association [2]
- Javits Neuroscience Investigator Award [3]
- The Harry B van Dyke Awards for Excellence in Medical Research (Pharmacology), Columbia University College of Physicians and Surgeons
- American Physiological Society Water B. Cannon Lecturer
- Recipient of American Heart Association Basic Research Prize
- Recipient of Louis and Artur Lucian Award for Research in Circulatory Diseases
- First Robert M. Berne Distinguished Lecturer of the American Physiological Society Cardiovascular Section [4]
- Newton-Abraham Visiting Professor in Medical, Biological and Chemical Sciences, (MA Honors), University of Oxford, England
Major contributions from his research laboratories to the field of ion channels include:
- Invention of ion-selective liquid exchanger microelectrodes [5] ;
- Description of membrane–delimited G protein effects on ion channels [5] ;
- Identification of the pore of voltage-gated and inwardly rectifying potassium channels [5] ;
- Specification of hERG potassium channel as lethal target for non-cardiac drugs, e.g., Seldane, Propulsid, etc. [5]
- Discovery of drug-induced block of hERG trafficking as cause of arrhythmias.
Dr. Brown is currently a collaborator with the US Federal Drug Administration (FDA) on cardiac safety issues. He holds nine patents on ion channel pharmacology, therapeutics and devices.
References[edit]
- ^ "2013 Distinguished Service Award Recipient". Retrieved 5 February 2014.
- ^ "The Rudy Clarenburg Lecture Series 1999". Retrieved 5 February 2014.
- ^ "College of Veterinary Medicine". Retrieved 5 February 2014.
- ^ "Recipients of the Robert M. Berne Distinguished Lectureship Award". Retrieved 5 February 2014.
- ^ a b c d Glaser, Vicki (2008 Dec). "An interview with Arthur M. "Buzz" Brown, M.D., Ph.D.". Assay and Drug Development Technologies. 6 (6): 737–42. doi:10.1089. PMID 19231939.
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